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KMT2D links TGF-β signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.
Lu S, Kim HS, Cao Y, Bedi K, Zhao L, Narayanan IV, Magnuson B, Gu Y, Yang J, Yi Z, Babaniamansour S, Shameon S, Xu C, Paulsen MT, Qiu P, Jeyarajan S, Ljungman M, Thomas D, Dou Y, Crawford H, di Magliano MP, Ge K, Yang B, Shi J. Lu S, et al. Among authors: shi j. Int J Cancer. 2023 Aug 1;153(3):552-570. doi: 10.1002/ijc.34528. Epub 2023 May 4. Int J Cancer. 2023. PMID: 37140208 Free PMC article.
HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM. Abel EV, et al. Among authors: shi j. Elife. 2018 Aug 3;7:e33947. doi: 10.7554/eLife.33947. Elife. 2018. PMID: 30074477 Free PMC article.
Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.
Zhang Q, Green MD, Lang X, Lazarus J, Parsels JD, Wei S, Parsels LA, Shi J, Ramnath N, Wahl DR, Pasca di Magliano M, Frankel TL, Kryczek I, Lei YL, Lawrence TS, Zou W, Morgan MA. Zhang Q, et al. Among authors: shi j. Cancer Res. 2019 Aug 1;79(15):3940-3951. doi: 10.1158/0008-5472.CAN-19-0761. Epub 2019 May 17. Cancer Res. 2019. PMID: 31101760 Free PMC article.
Mathematical Modeling of the Metastatic Colorectal Cancer Microenvironment Defines the Importance of Cytotoxic Lymphocyte Infiltration and Presence of PD-L1 on Antigen Presenting Cells.
Lazarus J, Oneka MD, Barua S, Maj T, Lanfranca MP, Delrosario L, Sun L, Smith JJ, D'Angelica MI, Shia J, Fang JM, Shi J, Di Magliano MP, Zou W, Rao A, Frankel TL. Lazarus J, et al. Among authors: shi j. Ann Surg Oncol. 2019 Sep;26(9):2821-2830. doi: 10.1245/s10434-019-07508-3. Epub 2019 Jun 27. Ann Surg Oncol. 2019. PMID: 31250346 Free PMC article.
Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice.
Perusina Lanfranca M, Zhang Y, Girgis A, Kasselman S, Lazarus J, Kryczek I, Delrosario L, Rhim A, Koneva L, Sartor M, Sun L, Halbrook C, Nathan H, Shi J, Crawford HC, Pasca di Magliano M, Zou W, Frankel TL. Perusina Lanfranca M, et al. Among authors: shi j. Gastroenterology. 2020 Apr;158(5):1417-1432.e11. doi: 10.1053/j.gastro.2019.12.010. Epub 2019 Dec 14. Gastroenterology. 2020. PMID: 31843590 Free PMC article.
An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development.
Shankar S, Tien JC, Siebenaler RF, Chugh S, Dommeti VL, Zelenka-Wang S, Wang XM, Apel IJ, Waninger J, Eyunni S, Xu A, Mody M, Goodrum A, Zhang Y, Tesmer JJ, Mannan R, Cao X, Vats P, Pitchiaya S, Ellison SJ, Shi J, Kumar-Sinha C, Crawford HC, Chinnaiyan AM. Shankar S, et al. Among authors: shi j. Nat Commun. 2020 Jun 4;11(1):2817. doi: 10.1038/s41467-020-16309-2. Nat Commun. 2020. PMID: 32499547 Free PMC article.
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