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Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Science. 2023 May 19;380(6646):eadh7699. doi: 10.1126/science.adh7699. Epub 2023 May 19.
Science. 2023.
PMID: 37141313
Free PMC article.
Transcriptome variation in human tissues revealed by long-read sequencing.
Glinos DA, Garborcauskas G, Hoffman P, Ehsan N, Jiang L, Gokden A, Dai X, Aguet F, Brown KL, Garimella K, Bowers T, Costello M, Ardlie K, Jian R, Tucker NR, Ellinor PT, Harrington ED, Tang H, Snyder M, Juul S, Mohammadi P, MacArthur DG, Lappalainen T, Cummings BB.
Glinos DA, et al.
Nature. 2022 Aug;608(7922):353-359. doi: 10.1038/s41586-022-05035-y. Epub 2022 Aug 3.
Nature. 2022.
PMID: 35922509
Free PMC article.
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Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants.
Einson J, Glinos D, Boerwinkle E, Castaldi P, Darbar D, de Andrade M, Ellinor P, Fornage M, Gabriel S, Germer S, Gibbs R, Hersh CP, Johnsen J, Kaplan R, Konkle BA, Kooperberg C, Nassir R, Loos RJF, Meyers DA, Mitchell BD, Psaty B, Vasan RS, Rich SS, Rienstra M, Rotter JI, Saferali A, Shoemaker MB, Silverman E, Smith AV; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Mohammadi P, Castel SE, Iossifov I, Lappalainen T.
Einson J, et al. Among authors: glinos d.
Genetics. 2023 Aug 9;224(4):iyad115. doi: 10.1093/genetics/iyad115.
Genetics. 2023.
PMID: 37348055
Free PMC article.
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Immune disease variants modulate gene expression in regulatory CD4+ T cells.
Bossini-Castillo L, Glinos DA, Kunowska N, Golda G, Lamikanra AA, Spitzer M, Soskic B, Cano-Gamez E, Smyth DJ, Cattermole C, Alasoo K, Mann A, Kundu K, Lorenc A, Soranzo N, Dunham I, Roberts DJ, Trynka G.
Bossini-Castillo L, et al. Among authors: glinos da.
Cell Genom. 2022 Apr 13;2(4):None. doi: 10.1016/j.xgen.2022.100117.
Cell Genom. 2022.
PMID: 35591976
Free PMC article.
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Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation.
Glinos DA, Soskic B, Williams C, Kennedy A, Jostins L, Sansom DM, Trynka G.
Glinos DA, et al.
Genes Immun. 2020 Dec;21(6-8):390-408. doi: 10.1038/s41435-020-00118-0. Epub 2020 Nov 23.
Genes Immun. 2020.
PMID: 33223527
Free PMC article.
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A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells.
Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, Fujita T, Fujii H, Liston A, Andrews S, Cozzani A, Yang J, Mitra S, Lugli E, Chang HY, Unutmaz D, Trynka G, Roychoudhuri R.
Nasrallah R, et al.
Nature. 2020 Jul;583(7816):447-452. doi: 10.1038/s41586-020-2296-7. Epub 2020 May 13.
Nature. 2020.
PMID: 32499651
Free PMC article.
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Immunogenomic approaches to understand the function of immune disease variants.
Glinos DA, Soskic B, Trynka G.
Glinos DA, et al.
Immunology. 2017 Dec;152(4):527-535. doi: 10.1111/imm.12796. Epub 2017 Aug 10.
Immunology. 2017.
PMID: 28718505
Free PMC article.
Review.
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Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events.
Wong VK, Baker S, Pickard DJ, Parkhill J, Page AJ, Feasey NA, Kingsley RA, Thomson NR, Keane JA, Weill FX, Edwards DJ, Hawkey J, Harris SR, Mather AE, Cain AK, Hadfield J, Hart PJ, Thieu NT, Klemm EJ, Glinos DA, Breiman RF, Watson CH, Kariuki S, Gordon MA, Heyderman RS, Okoro C, Jacobs J, Lunguya O, Edmunds WJ, Msefula C, Chabalgoity JA, Kama M, Jenkins K, Dutta S, Marks F, Campos J, Thompson C, Obaro S, MacLennan CA, Dolecek C, Keddy KH, Smith AM, Parry CM, Karkey A, Mulholland EK, Campbell JI, Dongol S, Basnyat B, Dufour M, Bandaranayake D, Naseri TT, Singh SP, Hatta M, Newton P, Onsare RS, Isaia L, Dance D, Davong V, Thwaites G, Wijedoru L, Crump JA, De Pinna E, Nair S, Nilles EJ, Thanh DP, Turner P, Soeng S, Valcanis M, Powling J, Dimovski K, Hogg G, Farrar J, Holt KE, Dougan G.
Wong VK, et al. Among authors: glinos da.
Nat Genet. 2015 Jun;47(6):632-9. doi: 10.1038/ng.3281. Epub 2015 May 11.
Nat Genet. 2015.
PMID: 25961941
Free PMC article.
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