Nørgaard A - Search Results

1

Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding.

Kulakova A, Augustijn D, El Bialy I, Gentiluomo L, Greco ML, Hervø-Hansen S, Indrakumar S, Mahapatra S, Martinez Morales M, Pohl C, Polimeni M, Roche A, Svilenov HL, Tosstorff A, Zalar M, Curtis R, Derrick JP, Frieß W, Golovanov AP, Lund M, Nørgaard A, Khan TA, Peters GHJ, Pluen A, Roessner D, Streicher WW, van der Walle CF, Warwicker J, Uddin S, Winter G, Bukrinski JT, Rinnan Å, Harris P. Kulakova A, et al. Among authors: norgaard a. Mol Pharm. 2023 Jun 5;20(6):2951-2965. doi: 10.1021/acs.molpharmaceut.3c00013. Epub 2023 May 5. Mol Pharm. 2023. PMID: 37146162

2

Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization.

Gentiluomo L, Svilenov HL, Augustijn D, El Bialy I, Greco ML, Kulakova A, Indrakumar S, Mahapatra S, Morales MM, Pohl C, Roche A, Tosstorff A, Curtis R, Derrick JP, Nørgaard A, Khan TA, Peters GHJ, Pluen A, Rinnan Å, Streicher WW, van der Walle CF, Uddin S, Winter G, Roessner D, Harris P, Frieß W. Gentiluomo L, et al. Among authors: norgaard a. Mol Pharm. 2020 Feb 3;17(2):426-440. doi: 10.1021/acs.molpharmaceut.9b00852. Epub 2020 Jan 7. Mol Pharm. 2020. PMID: 31790599

3

Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR.

Indrakumar S, Zalar M, Pohl C, Nørgaard A, Streicher W, Harris P, Golovanov AP, Peters GHJ. Indrakumar S, et al. Among authors: norgaard a. J Phys Chem B. 2019 Jun 13;123(23):4867-4877. doi: 10.1021/acs.jpcb.9b02370. Epub 2019 May 31. J Phys Chem B. 2019. PMID: 31099578

4

Development of a fast screening method for selecting excipients in formulations using MD simulations, NMR and microscale thermophoresis.

Indrakumar S, Zalar M, Tschammer N, Pohl C, Nørgaard A, Streicher W, Harris P, Golovanov AP, Peters GHJ. Indrakumar S, et al. Among authors: norgaard a. Eur J Pharm Biopharm. 2021 Jan;158:11-20. doi: 10.1016/j.ejpb.2020.10.015. Epub 2020 Nov 1. Eur J Pharm Biopharm. 2021. PMID: 33137420

5

Combination of high throughput and structural screening to assess protein stability - A screening perspective.

Pohl C, Mahapatra S, Kulakova A, Streicher W, Peters GHJ, Nørgaard A, Harris P. Pohl C, et al. Among authors: norgaard a. Eur J Pharm Biopharm. 2022 Feb;171:1-10. doi: 10.1016/j.ejpb.2021.08.018. Epub 2021 Nov 23. Eur J Pharm Biopharm. 2022. PMID: 34826593 Free article.

6

Electrostatics Drive Oligomerization and Aggregation of Human Interferon Alpha-2a.

Pohl C, Polimeni M, Indrakumar S, Streicher W, Peters GHJ, Nørgaard A, Lund M, Harris P. Pohl C, et al. Among authors: norgaard a. J Phys Chem B. 2021 Dec 23;125(50):13657-13669. doi: 10.1021/acs.jpcb.1c07090. Epub 2021 Dec 13. J Phys Chem B. 2021. PMID: 34898211 Free PMC article.

7

Sequential unfolding of the two-domain protein Pseudomonas stutzeri cytochrome c(4).

Andersen NH, Nørgaard A, Jensen TJ, Ulstrup J. Andersen NH, et al. Among authors: norgaard a. J Inorg Biochem. 2002 Feb;88(3-4):316-27. doi: 10.1016/s0162-0134(01)00358-0. J Inorg Biochem. 2002. PMID: 11897346

8

Expression of recombinant Pseudomonas stutzeri di-heme cytochrome c4 by high-cell-density fed-batch cultivation of Pseudomonas putida.

Thuesen MH, Nørgaard A, Hansen AM, Caspersen MB, Christensen HE. Thuesen MH, et al. Among authors: norgaard a. Protein Expr Purif. 2003 Jan;27(1):175-81. doi: 10.1016/s1046-5928(02)00575-2. Protein Expr Purif. 2003. PMID: 12510001

9

The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium.

Moroz OV, Blagova E, Lebedev AA, Nørgaard A, Segura DR, Blicher TH, Brask J, Wilson KS. Moroz OV, et al. Among authors: norgaard a. Acta Crystallogr D Struct Biol. 2017 Jan 1;73(Pt 1):32-44. doi: 10.1107/S2059798316019616. Epub 2017 Jan 1. Acta Crystallogr D Struct Biol. 2017. PMID: 28045383

10

Characteristics and Management of Chorioamnionitis at an Academic Centre in Ontario Before and After Implementation of an Order Set.

Kay VR, Liang I, Turvey S, Vandersluis A, Norgaard A, Twiss J, Morais M. Kay VR, et al. Among authors: norgaard a. J Obstet Gynaecol Can. 2024 Jun;46(6):102430. doi: 10.1016/j.jogc.2024.102430. Epub 2024 Mar 4. J Obstet Gynaecol Can. 2024. PMID: 38447667

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