Caldas IS - Search Results

1

New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis.

Campos Péret VA, Reis RCFM, Braga SFP, Benedetti MD, Caldas IS, Carvalho DT, Santana LFA, Johann S, Souza TB. Campos Péret VA, et al. Among authors: caldas is. Eur J Med Chem. 2023 Aug 5;256:115436. doi: 10.1016/j.ejmech.2023.115436. Epub 2023 May 1. Eur J Med Chem. 2023. PMID: 37146343

2

In vitro and in vivo trypanocidal activities of 8-methoxy-3-(4-nitrobenzoyl)-6-propyl-2H-cromen-2-one, a new synthetic coumarin of low cytotoxicity against mammalian cells.

Brancaglion GA, Toyota AE, Cardoso Machado JV, Fernandes Júnior AÁ, Silveira AT, Vilas Boas DF, Dos Santos EG, Caldas IS, Carvalho DT. Brancaglion GA, et al. Among authors: caldas is. Chem Biol Drug Des. 2018 Nov;92(5):1888-1898. doi: 10.1111/cbdd.13362. Epub 2018 Jul 27. Chem Biol Drug Des. 2018. PMID: 29992719

3

Synthesis, activity, and molecular modeling studies of 1,2,3-triazole derivatives from natural phenylpropanoids as new trypanocidal agents.

de Souza TB, Caldas IS, Paula FR, Rodrigues CC, Carvalho DT, Dias DF. de Souza TB, et al. Among authors: caldas is. Chem Biol Drug Des. 2020 Jan;95(1):124-129. doi: 10.1111/cbdd.13628. Epub 2019 Oct 20. Chem Biol Drug Des. 2020. PMID: 31569301

4

Synthesis of New Hybrid Derivatives from Metronidazole and Eugenol Analogues as Trypanocidal Agents.

Pelozo MF, Lima GFS, Cordeiro CF, Silva LS, Caldas IS, Carvalho DT, Lavorato SN, Hawkes JA, Franco LL. Pelozo MF, et al. Among authors: caldas is. J Pharm Pharm Sci. 2021;24:421-434. doi: 10.18433/jpps31839. J Pharm Pharm Sci. 2021. PMID: 34410908 Free article.

5

4-nitrobenzoylcoumarin potentiates the antiparasitic, anti-inflammatory and cardioprotective effects of benznidazole in a murine model of acute Trypanosoma cruzi infection.

Vilas-Boas DF, Oliveira RRG, Gonçalves-Santos E, Silva LS, Diniz LF, Mazzeti AL, Brancaglion GA, Carvalho DT, Caldas S, Novaes RD, Caldas IS. Vilas-Boas DF, et al. Among authors: caldas s, caldas is. Acta Trop. 2022 Apr;228:106314. doi: 10.1016/j.actatropica.2022.106314. Epub 2022 Jan 15. Acta Trop. 2022. PMID: 35038424 Free article.

6

Design and synthesis of new 1,2,3-triazoles derived from eugenol and analogues with in vitro and in vivo activity against Trypanosoma cruzi.

Reis RCFM, Dos Santos EG, Benedetti MD, Reis ACC, Brandão GC, Silva GND, Diniz LA, Ferreira RS, Caldas IS, Braga SFP, Souza TB. Reis RCFM, et al. Among authors: caldas is. Eur J Med Chem. 2023 Oct 5;258:115622. doi: 10.1016/j.ejmech.2023.115622. Epub 2023 Jul 11. Eur J Med Chem. 2023. PMID: 37441850

7

Schistosoma mansoni co-infection modulates Chagas disease development but does not impair the effect of benznidazole-based chemotherapy.

Lozano KJG, Gonçalves Santos E, Vilas Boas DF, Oliveira RRG, Diniz LF, Benedetti MD, Carneiro CM, C Bandeira L, Faria G, Gonçalves RV, Novaes RD, Caldas S, Caldas IS. Lozano KJG, et al. Among authors: caldas is. Int Immunopharmacol. 2024 Feb 15;128:111467. doi: 10.1016/j.intimp.2023.111467. Epub 2024 Jan 10. Int Immunopharmacol. 2024. PMID: 38211479

8

Synthesis of new trypanocidal agents from the hybridisation of metronidazole and eugenol analogues.

Pelozo MF, Cordeiro CF, Inácio LF, de Cassia Alves Lemini R, Gonçalves Souza E Leite E, Benedetti MD, Tulha CA, Novaes RD, Caldas IS, Carvalho DT, Lavorato SN, Hawkes JA, Franco LL. Pelozo MF, et al. Among authors: caldas is. Bioorg Chem. 2024 May;146:107288. doi: 10.1016/j.bioorg.2024.107288. Epub 2024 Mar 15. Bioorg Chem. 2024. PMID: 38521013

9

Discovery of a new eugenol-benznidazole hybrid active against different evolutive stages of Trypanosoma cruzi.

de Melo ÍM, Camargo TP, da Silva VA, Dos Santos EG, Caldas IS, Mansur Pontes CL, Stoco PH, de Menezes Vaidergorn M, Nonato MC, de Souza TB. de Melo ÍM, et al. Among authors: caldas is. Bioorg Chem. 2025 Jan;154:107993. doi: 10.1016/j.bioorg.2024.107993. Epub 2024 Nov 22. Bioorg Chem. 2025. PMID: 39591688

10

Retinol-binding protein 4 and insulin resistance are related to body fat in primary and secondary schoolchildren: the Ouro Preto study.

Castro AP, Cândido AP, Nicolato RL, Caldas IS, Machado-Coelho GL. Castro AP, et al. Among authors: caldas is. Eur J Nutr. 2014;53(2):433-40. doi: 10.1007/s00394-013-0543-5. Epub 2013 Jun 14. Eur J Nutr. 2014. PMID: 23764679

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