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New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis.
Eur J Med Chem. 2023 Aug 5;256:115436. doi: 10.1016/j.ejmech.2023.115436. Epub 2023 May 1.
Eur J Med Chem. 2023.
PMID: 37146343
Glucosyl-1,2,3-triazoles derived from eugenol and analogues: Synthesis, anti-Candida activity, and molecular modeling studies in CYP-51.
Magalhães LS, Reis ACC, Nakao IA, Péret VAC, Reis RCFM, Silva NC, Dias ALT, Carvalho DT, Dias DF, Brandão GC, Braga SFP, Souza TB.
Magalhães LS, et al. Among authors: reis rcfm.
Chem Biol Drug Des. 2021 Nov;98(5):903-913. doi: 10.1111/cbdd.13948. Epub 2021 Sep 12.
Chem Biol Drug Des. 2021.
PMID: 34480517
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Design and synthesis of new 1,2,3-triazoles derived from eugenol and analogues with in vitro and in vivo activity against Trypanosoma cruzi.
Reis RCFM, Dos Santos EG, Benedetti MD, Reis ACC, Brandão GC, Silva GND, Diniz LA, Ferreira RS, Caldas IS, Braga SFP, Souza TB.
Reis RCFM, et al.
Eur J Med Chem. 2023 Oct 5;258:115622. doi: 10.1016/j.ejmech.2023.115622. Epub 2023 Jul 11.
Eur J Med Chem. 2023.
PMID: 37441850
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