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Combination therapy with anti-programmed cell death 1 antibody plus angiokinase inhibitor exerts synergistic antitumor effect against malignant mesothelioma via tumor microenvironment modulation.
Tada A, Minami T, Kitai H, Higashiguchi Y, Tokuda M, Higashiyama T, Negi Y, Horio D, Nakajima Y, Otsuki T, Mikami K, Takahashi R, Nakamura A, Kitajima K, Ohmuraya M, Kuribayashi K, Kijima T. Tada A, et al. Among authors: higashiyama t. Lung Cancer. 2023 Jun;180:107219. doi: 10.1016/j.lungcan.2023.107219. Epub 2023 Apr 26. Lung Cancer. 2023. PMID: 37146474 Free article.
The peri-germ cell membrane: poorly characterized but key interface for plant reproduction.
Sugi N, Calhau ARM, Jacquier NMA, Millan-Blanquez M, Becker JD, Begcy K, Berger F, Bousquet-Antonelli C, Bouyer D, Cai G, Cheung AY, Coimbra S, Denninger P, Dresselhaus T, Feijó JA, Fowler JE, Geelen D, Grossniklaus U, Higashiyama T, Honys D, Igawa T, Ingram G, Jaillais Y, Johnson MA, Kato M, Kawachi M, Kawashima T, Kim YJ, Li HJ, Mongrand S, Motomura K, Nagahara S, Nakajima KP, Nelms B, Qu LJ, Schnittger A, Scholten S, Sprunck S, Sun MX, Twell D, Weijers D, Yang WC, Maruyama D, Widiez T. Sugi N, et al. Among authors: higashiyama t. Nat Plants. 2024 Oct 15. doi: 10.1038/s41477-024-01818-5. Online ahead of print. Nat Plants. 2024. PMID: 39406861 No abstract available.
Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose.
Tung HC, Kim JW, Zhu J, Li S, Yan J, Liu Q, Koo I, Koshkin SA, Hao F, Zhong G, Xu M, Wang Z, Wang J, Huang Y, Xi Y, Cai X, Xu P, Ren S, Higashiyama T, Gonzalez FJ, Li S, Isoherranen N, Yang D, Ma X, Patterson AD, Xie W. Tung HC, et al. Among authors: higashiyama t. Sci Transl Med. 2024 Sep 25;16(766):eadk8446. doi: 10.1126/scitranslmed.adk8446. Epub 2024 Sep 25. Sci Transl Med. 2024. PMID: 39321267
PD-L1 Expression and Its Modulating Factors in Anaplastic Thyroid Carcinoma: A Multi-institutional Study.
Agarwal S, Jung CK, Gaddam P, Hirokawa M, Higashiyama T, Hang JF, Lai WA, Keelawat S, Liu Z, Na HY, Park SY, Fukuoka J, Satoh S, Mussazhanova Z, Nakashima M, Kakudo K, Bychkov A. Agarwal S, et al. Among authors: higashiyama t. Am J Surg Pathol. 2024 Oct 1;48(10):1233-1244. doi: 10.1097/PAS.0000000000002284. Epub 2024 Jul 15. Am J Surg Pathol. 2024. PMID: 39004795
393 results