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Dual targeted 2-Benzylideneindanone pendant hydroxamic acid group exhibits selective HDAC6 inhibition along with tubulin stabilization effect.
Kumar K, Das R, Thapa B, Rakhecha B, Srivastava S, Savita K, Israr M, Chanda D, Banerjee D, Shanker K, Bawankule DU, Santini B, Di Paolo ML, Via LD, Passarella D, Negi AS. Kumar K, et al. Among authors: passarella d. Bioorg Med Chem. 2023 May 15;86:117300. doi: 10.1016/j.bmc.2023.117300. Epub 2023 Apr 27. Bioorg Med Chem. 2023. PMID: 37146520
Click Reaction as a Tool to Combine Pharmacophores: The Case of Vismodegib.
Christodoulou MS, Mori M, Pantano R, Alfonsi R, Infante P, Botta M, Damia G, Ricci F, Sotiropoulou PA, Liekens S, Botta B, Passarella D. Christodoulou MS, et al. Among authors: passarella d. Chempluschem. 2015 Jun;80(6):938-943. doi: 10.1002/cplu.201402435. Epub 2015 Feb 27. Chempluschem. 2015. PMID: 31973263
Chalcone Derivatives Activate and Desensitize the Transient Receptor Potential Ankyrin 1 Cation Channel, Subfamily A, Member 1 TRPA1 Ion Channel: Structure-Activity Relationships in vitro and Anti-Nociceptive and Anti-inflammatory Activity in vivo.
Moriello AS, Luongo L, Guida F, Christodoulou MS, Perdicchia D, Maione S, Passarella D, Marzo VD, Petrocellis L. Moriello AS, et al. Among authors: passarella d. CNS Neurol Disord Drug Targets. 2016;15(8):987-994. doi: 10.2174/1871527315666160413123621. CNS Neurol Disord Drug Targets. 2016. PMID: 27071783 Free article.
Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors.
Visentin C, Musso L, Broggini L, Bonato F, Russo R, Moriconi C, Bolognesi M, Miranda E, Dallavalle S, Passarella D, Ricagno S. Visentin C, et al. Among authors: passarella d. Life (Basel). 2020 Jul 11;10(7):111. doi: 10.3390/life10070111. Life (Basel). 2020. PMID: 32664592 Free PMC article.
129 results