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Dual targeted 2-Benzylideneindanone pendant hydroxamic acid group exhibits selective HDAC6 inhibition along with tubulin stabilization effect.
Kumar K, Das R, Thapa B, Rakhecha B, Srivastava S, Savita K, Israr M, Chanda D, Banerjee D, Shanker K, Bawankule DU, Santini B, Di Paolo ML, Via LD, Passarella D, Negi AS. Kumar K, et al. Among authors: via ld. Bioorg Med Chem. 2023 May 15;86:117300. doi: 10.1016/j.bmc.2023.117300. Epub 2023 Apr 27. Bioorg Med Chem. 2023. PMID: 37146520
Synthesis and biological evaluation of pyrroloiminoquinone derivatives.
Passarella D, Belinghieri F, Scarpellini M, Pratesi G, Zunino F, Gia OM, Via LD, Santoro G, Danieli B. Passarella D, et al. Among authors: via ld. Bioorg Med Chem. 2008 Mar 1;16(5):2431-8. doi: 10.1016/j.bmc.2007.11.063. Epub 2007 Nov 28. Bioorg Med Chem. 2008. PMID: 18077173
Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates To Overcome Cancer Resistance.
Fumagalli G, Giorgi G, Vágvölgyi M, Colombo E, Christodoulou MS, Collico V, Prosperi D, Dosio F, Hunyadi A, Montopoli M, Hyeraci M, Silvani A, Lesma G, Via LD, Passarella D. Fumagalli G, et al. Among authors: via ld. ACS Med Chem Lett. 2018 Apr 17;9(5):468-471. doi: 10.1021/acsmedchemlett.8b00078. eCollection 2018 May 10. ACS Med Chem Lett. 2018. PMID: 29795761 Free PMC article.
Targeting multiple G-quadruplex-forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives.
Catalano R, Moraca F, Amato J, Cristofari C, Rigo R, Via LD, Rocca R, Lupia A, Maruca A, Costa G, Catalanotti B, Artese A, Pagano B, Randazzo A, Sissi C, Novellino E, Alcaro S. Catalano R, et al. Among authors: via ld. Eur J Med Chem. 2019 Nov 15;182:111627. doi: 10.1016/j.ejmech.2019.111627. Epub 2019 Aug 16. Eur J Med Chem. 2019. PMID: 31446246
21 results