Gao G - Search Results

1

Renewal of oligodendrocyte lineage reverses dysmyelination and CNS neurodegeneration through corrected N-acetylaspartate metabolism.

Lotun A, Li D, Xu H, Su Q, Tuncer S, Sanmiguel J, Mooney M, Baer CE, Ulbrich R, Eyles SJ, Strittmatter L, Hayward LJ, Gessler DJ, Gao G. Lotun A, et al. Among authors: gao g. Prog Neurobiol. 2023 Jul;226:102460. doi: 10.1016/j.pneurobio.2023.102460. Epub 2023 May 4. Prog Neurobiol. 2023. PMID: 37149081 Free PMC article.

2

Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.

Werneburg S, Jung J, Kunjamma RB, Ha SK, Luciano NJ, Willis CM, Gao G, Biscola NP, Havton LA, Crocker SJ, Popko B, Reich DS, Schafer DP. Werneburg S, et al. Among authors: gao g. Immunity. 2020 Jan 14;52(1):167-182.e7. doi: 10.1016/j.immuni.2019.12.004. Epub 2019 Dec 26. Immunity. 2020. PMID: 31883839 Free PMC article.

3

Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope.

Bamidele N, Zhang H, Dong X, Gaston N, Cheng H, Kelly K, Watts JK, Xie J, Gao G, Sontheimer EJ. Bamidele N, et al. Among authors: gao g. bioRxiv [Preprint]. 2023 Apr 18:2023.04.14.536905. doi: 10.1101/2023.04.14.536905. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 17;15(1):1458. doi: 10.1038/s41467-024-45763-5 PMID: 37131611 Free PMC article. Updated. Preprint.

4

AAV-Mediated Targeting of the Activin A-ACVR1^R206H Signaling in Fibrodysplasia Ossificans Progressiva.

Yang YS, Lin C, Ma H, Xie J, Kaplan FS, Gao G, Shim JH. Yang YS, et al. Among authors: gao g. Biomolecules. 2023 Sep 8;13(9):1364. doi: 10.3390/biom13091364. Biomolecules. 2023. PMID: 37759764 Free PMC article.

5

NIIMBL's viral vector program: A cross-gene therapy community collaboration to transform viral vector development and manufacturing.

Lee KH, Gao G. Lee KH, et al. Among authors: gao g. Mol Ther. 2023 Dec 6;31(12):3359-3360. doi: 10.1016/j.ymthe.2023.11.009. Epub 2023 Nov 21. Mol Ther. 2023. PMID: 37989318 Free PMC article. No abstract available.

6

Engineering a targeted and safe bone anabolic gene therapy to treat osteoporosis in alveolar bone loss.

Lin C, Yang YS, Ma H, Chen Z, Chen D, John AA, Xie J, Gao G, Shim JH. Lin C, et al. Among authors: gao g. Mol Ther. 2024 Sep 4;32(9):3080-3100. doi: 10.1016/j.ymthe.2024.06.036. Epub 2024 Jun 26. Mol Ther. 2024. PMID: 38937970 Free PMC article.

7

AAV-based gene editing of type 1 collagen mutation to treat osteogenesis imperfecta.

Yang YS, Sato T, Chaugule S, Ma H, Xie J, Gao G, Shim JH. Yang YS, et al. Among authors: gao g. Mol Ther Nucleic Acids. 2023 Dec 26;35(1):102111. doi: 10.1016/j.omtn.2023.102111. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2023. PMID: 38261950 Free PMC article.

8

A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors.

Chen Z, Kwan SY, Mir A, Hazeltine M, Shin M, Liang SQ, Chan IL, Kelly K, Ghanta KS, Gaston N, Cao Y, Xie J, Gao G, Xue W, Sontheimer EJ, Watts JK. Chen Z, et al. Among authors: gao g. CRISPR J. 2023 Dec;6(6):570-582. doi: 10.1089/crispr.2023.0048. CRISPR J. 2023. PMID: 38108517 Free PMC article.

9

Oligonucleotide therapies for nonalcoholic steatohepatitis.

Li S, Xiong F, Zhang S, Liu J, Gao G, Xie J, Wang Y. Li S, et al. Among authors: gao g. Mol Ther Nucleic Acids. 2024 Mar 30;35(2):102184. doi: 10.1016/j.omtn.2024.102184. eCollection 2024 Jun 11. Mol Ther Nucleic Acids. 2024. PMID: 38665220 Free PMC article. Review.

10

The 2024 Nobel Prize: Impact of the Discovery of miRNA on the Field of Gene Therapy.

Mueller C, Gao G, Flotte TR. Mueller C, et al. Among authors: gao g. Hum Gene Ther. 2025 Jan 3. doi: 10.1089/hum.2024.98457. Online ahead of print. Hum Gene Ther. 2025. PMID: 39752182 No abstract available.

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