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Page 1
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.
Berard AR, Brubaker DK, Birse K, Lamont A, Mackelprang RD, Noël-Romas L, Perner M, Hou X, Irungu E, Mugo N, Knodel S, Muwonge TR, Katabira E, Hughes SM, Levy C, Calienes FL, Lauffenburger DA, Baeten JM, Celum C, Hladik F, Lingappa J, Burgener AD. Berard AR, et al. Among authors: perner m. Cell Rep. 2023 May 30;42(5):112474. doi: 10.1016/j.celrep.2023.112474. Epub 2023 May 6. Cell Rep. 2023. PMID: 37149863 Free PMC article.
Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women.
Klatt NR, Cheu R, Birse K, Zevin AS, Perner M, Noël-Romas L, Grobler A, Westmacott G, Xie IY, Butler J, Mansoor L, McKinnon LR, Passmore JS, Abdool Karim Q, Abdool Karim SS, Burgener AD. Klatt NR, et al. Among authors: perner m. Science. 2017 Jun 2;356(6341):938-945. doi: 10.1126/science.aai9383. Science. 2017. PMID: 28572388
Plasma concentration of injectable contraceptive correlates with reduced cervicovaginal growth factor expression in South African women.
Molatlhegi RP, Liebenberg LJ, Leslie A, Noel-Romas L, Mabhula A, Mchunu N, Perner M, Birse K, Ngcapu S, Adamson JH, Govender K, Garrett NJ, Samsunder N, Burgener AD, Abdool Karim SS, Abdool Karim Q, Passmore JS, McKinnon LR. Molatlhegi RP, et al. Among authors: perner m. Mucosal Immunol. 2020 May;13(3):449-459. doi: 10.1038/s41385-019-0249-y. Epub 2020 Jan 2. Mucosal Immunol. 2020. PMID: 31896762 Free article.
Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition.
Noël-Romas L, Perner M, Molatlhegi R, Farr Zuend C, Mabhula A, Hoger S, Lamont A, Birse K, Berard A, McCorrister S, Westmacott G, Leslie A, Poliquin V, Heffron R, McKinnon LR, Burgener AD. Noël-Romas L, et al. Among authors: perner m. PLoS Pathog. 2020 Dec 23;16(12):e1009097. doi: 10.1371/journal.ppat.1009097. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33362285 Free PMC article.
Non-Lactobacillus-Dominant and Polymicrobial Vaginal Microbiomes Are More Common in Younger South African Women and Predictive of Increased Risk of Human Immunodeficiency Virus Acquisition.
Wang Y, Noël-Romas L, Perner M, Knodel S, Molatlhegi R, Hoger S, Birse K, Zuend CF, McKinnon LR, Burgener AD. Wang Y, et al. Among authors: perner m. Clin Infect Dis. 2023 Apr 17;76(8):1372-1381. doi: 10.1093/cid/ciac938. Clin Infect Dis. 2023. PMID: 36504254 Free PMC article. Clinical Trial.
Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus.
Farr Zuend C, Lamont A, Noel-Romas L, Knodel S, Birse K, Kratzer K, McQueen P, Perner M, Ayele H, Mutch S, Berard AR, Schellenberg JJ, Senturk F, McCorrister S, Westmacott G, Mulhall F, Sandberg B, Yu A, Burnett M, Poliquin V, Burgener AD. Farr Zuend C, et al. Among authors: perner m. Microbiome. 2023 Jul 25;11(1):159. doi: 10.1186/s40168-023-01594-y. Microbiome. 2023. PMID: 37491398 Free PMC article.
Endocervical Regulatory T Cells Are Associated With Decreased Genital Inflammation and Lower HIV Target Cell Abundance.
Ssemaganda A, Cholette F, Perner M, Kambaran C, Adhiambo W, Wambugu PM, Gebrebrhan H, Lee A, Nuhu F, Mwatelah RS, Jahan N, Omole TE, Wanjiru T, Gitau A, Kimani J, McKinnon LR. Ssemaganda A, et al. Among authors: perner m. Front Immunol. 2021 Sep 23;12:726472. doi: 10.3389/fimmu.2021.726472. eCollection 2021. Front Immunol. 2021. PMID: 34630402 Free PMC article.
Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites.
Lawore DC, Jena S, Berard AR, Birse K, Lamont A, Mackelprang RD, Noel-Romas L, Perner M, Hou X, Irungu E, Mugo N, Knodel S, Muwonge TR, Katabira E, Hughes SM, Levy C, Calienes FL, Hladik F, Lingappa JR, Burgener AD, Green LN, Brubaker DK. Lawore DC, et al. Among authors: perner m. bioRxiv [Preprint]. 2024 Oct 17:2024.10.10.616351. doi: 10.1101/2024.10.10.616351. bioRxiv. 2024. PMID: 39416028 Free PMC article. Preprint.
57 results