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Selective and brain-penetrant ACSS2 inhibitors target breast cancer brain metastatic cells.
Esquea EM, Ciraku L, Young RG, Merzy J, Talarico AN, Ahmed NN, Karuppiah M, Ramesh A, Chatoff A, Crispim CV, Rashad AA, Cocklin S, Snyder NW, Beld J, Simone NL, Reginato MJ, Dick A. Esquea EM, et al. Among authors: snyder nw. Front Pharmacol. 2024 May 16;15:1394685. doi: 10.3389/fphar.2024.1394685. eCollection 2024. Front Pharmacol. 2024. PMID: 38818373 Free PMC article.
Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production.
Sharrow AC, Megill E, Chen AJ, Farooqi A, Tangudu NK, Uboveja A, McGonigal S, Hempel N, Snyder NW, Buckanovich RJ, Aird KM. Sharrow AC, et al. Among authors: snyder nw. Mol Metab. 2024 Nov;89:102031. doi: 10.1016/j.molmet.2024.102031. Epub 2024 Sep 19. Mol Metab. 2024. PMID: 39304063 Free PMC article.
Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.
Drummer C 4th, Saaoud F, Jhala NC, Cueto R, Sun Y, Xu K, Shao Y, Lu Y, Shen H, Yang L, Zhou Y, Yu J, Wu S, Snyder NW, Hu W, Zhuo J', Zhong Y, Jiang X, Wang H, Yang X. Drummer C 4th, et al. Among authors: snyder nw. Front Immunol. 2023 Jan 26;14:1113883. doi: 10.3389/fimmu.2023.1113883. eCollection 2023. Front Immunol. 2023. PMID: 36776889 Free PMC article.
Comparison of colorimetric, fluorometric, and liquid chromatography-mass spectrometry assays for acetyl-coenzyme A.
Kantner DS, Megill E, Bostwick A, Yang V, Bekeova C, Van Scoyk A, Seifert E, Deininger MW, Snyder NW. Kantner DS, et al. Among authors: snyder nw. bioRxiv [Preprint]. 2023 Aug 15:2023.06.01.543311. doi: 10.1101/2023.06.01.543311. bioRxiv. 2023. Update in: Anal Biochem. 2024 Jan 15;685:115405. doi: 10.1016/j.ab.2023.115405 PMID: 37398224 Free PMC article. Updated. Preprint.
Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase.
Liu JY, Kuna RS, Pinheiro LV, Nguyen PTT, Welles JE, Drummond JM, Murali N, Sharma PV, Supplee JG, Shiue M, Zhao S, Farria AT, Kumar A, Ruchhoeft ML, Demetriadou C, Kantner DS, Chatoff A, Megill E, Titchenell PM, Snyder NW, Metallo CM, Wellen KE. Liu JY, et al. Among authors: snyder nw. Cell Metab. 2025 Jan 7;37(1):239-254.e7. doi: 10.1016/j.cmet.2024.10.014. Epub 2024 Oct 28. Cell Metab. 2025. PMID: 39471816
ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development.
Lu Y, Sun Y, Saaoud F, Shao Y, Xu K, Jiang X, Wu S, Yu J, Snyder NW, Yang L, Shi XM, Zhao H, Wang H, Yang X. Lu Y, et al. Among authors: snyder nw. Front Immunol. 2023 Sep 4;14:1268916. doi: 10.3389/fimmu.2023.1268916. eCollection 2023. Front Immunol. 2023. PMID: 37731512 Free PMC article.
142 results