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Targeted locus amplification to develop robust patient-specific assays for liquid biopsies in pediatric solid tumors.
van Zogchel LMJ, Lak NSM, Gelineau NU, Sergeeva I, Stelloo E, Swennenhuis J, Feitsma H, van Min M, Splinter E, Bleijs M, Groot Koerkamp M, Breunis W, Meister MT, Kholossy WH, Holstege FCP, Molenaar JJ, de Leng WWJ, Stutterheim J, van der Schoot CE, Tytgat GAM. van Zogchel LMJ, et al. Among authors: tytgat gam. Front Oncol. 2023 Apr 20;13:1124737. doi: 10.3389/fonc.2023.1124737. eCollection 2023. Front Oncol. 2023. PMID: 37152023 Free PMC article.
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations.
Eleveld TF, Oldridge DA, Bernard V, Koster J, Colmet Daage L, Diskin SJ, Schild L, Bentahar NB, Bellini A, Chicard M, Lapouble E, Combaret V, Legoix-Né P, Michon J, Pugh TJ, Hart LS, Rader J, Attiyeh EF, Wei JS, Zhang S, Naranjo A, Gastier-Foster JM, Hogarty MD, Asgharzadeh S, Smith MA, Guidry Auvil JM, Watkins TB, Zwijnenburg DA, Ebus ME, van Sluis P, Hakkert A, van Wezel E, van der Schoot CE, Westerhout EM, Schulte JH, Tytgat GA, Dolman ME, Janoueix-Lerosey I, Gerhard DS, Caron HN, Delattre O, Khan J, Versteeg R, Schleiermacher G, Molenaar JJ, Maris JM. Eleveld TF, et al. Nat Genet. 2015 Aug;47(8):864-71. doi: 10.1038/ng.3333. Epub 2015 Jun 29. Nat Genet. 2015. PMID: 26121087 Free PMC article.
Neuroblastoma is composed of two super-enhancer-associated differentiation states.
van Groningen T, Koster J, Valentijn LJ, Zwijnenburg DA, Akogul N, Hasselt NE, Broekmans M, Haneveld F, Nowakowska NE, Bras J, van Noesel CJM, Jongejan A, van Kampen AH, Koster L, Baas F, van Dijk-Kerkhoven L, Huizer-Smit M, Lecca MC, Chan A, Lakeman A, Molenaar P, Volckmann R, Westerhout EM, Hamdi M, van Sluis PG, Ebus ME, Molenaar JJ, Tytgat GA, Westerman BA, van Nes J, Versteeg R. van Groningen T, et al. Nat Genet. 2017 Aug;49(8):1261-1266. doi: 10.1038/ng.3899. Epub 2017 Jun 26. Nat Genet. 2017. PMID: 28650485
Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study.
Van Paemel R, De Koker A, Vandeputte C, van Zogchel L, Lammens T, Laureys G, Vandesompele J, Schleiermacher G, Chicard M, Van Roy N, Vicha A, Tytgat GAM, Callewaert N, De Preter K, De Wilde B. Van Paemel R, et al. Among authors: tytgat gam. Epigenetics. 2021 Jan-Feb;16(2):196-208. doi: 10.1080/15592294.2020.1790950. Epub 2020 Jul 14. Epigenetics. 2021. PMID: 32662719 Free PMC article.
The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples.
Van Paemel R, Vandeputte C, Raman L, Van Thorre J, Willems L, Van Dorpe J, Van Der Linden M, De Wilde J, De Koker A, Menten B, Devalck C, Vicha A, Grega M, Schleiermacher G, Iddir Y, Chicard M, van Zogchel L, Stutterheim J, Lak NSM, Tytgat GAM, Laureys G, Speleman F, De Wilde B, Lammens T, De Preter K, Van Roy N. Van Paemel R, et al. Among authors: tytgat gam. Eur J Cancer. 2022 Jan;160:12-23. doi: 10.1016/j.ejca.2021.09.022. Epub 2021 Nov 16. Eur J Cancer. 2022. PMID: 34794856 Free article.
Novel Circulating Hypermethylated RASSF1A ddPCR for Liquid Biopsies in Patients With Pediatric Solid Tumors.
van Zogchel LMJ, Lak NSM, Verhagen OJHM, Tissoudali A, Gussmalla Nuru M, Gelineau NU, Zappeij-Kannengieter L, Javadi A, Zijtregtop EAM, Merks JHM, van den Heuvel-Eibrink M, Schouten-van Meeteren AYN, Stutterheim J, van der Schoot CE, Tytgat GAM. van Zogchel LMJ, et al. Among authors: tytgat gam. JCO Precis Oncol. 2021 Nov 17;5:PO.21.00130. doi: 10.1200/PO.21.00130. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34820594 Free PMC article.
A Common Genomic Denominator for Neuroblastoma and Differentiated Thyroid Carcinoma? A Case Series in Children.
Clement SC, Koster J, Kuiper RP, Tytgat GAM, Ebus ME, Schild L, Gilissen C, Zwijnenburg DA, Versteeg R, Molenaar JJ, van Santen HM. Clement SC, et al. Among authors: tytgat gam. Clin Oncol (R Coll Radiol). 2022 Jul;34(7):e318-e319. doi: 10.1016/j.clon.2022.03.016. Epub 2022 Apr 7. Clin Oncol (R Coll Radiol). 2022. PMID: 35400598 No abstract available.
Cell-Free DNA as a Diagnostic and Prognostic Biomarker in Pediatric Rhabdomyosarcoma.
Lak NSM, van Zogchel LMJ, Zappeij-Kannegieter L, Javadi A, van Paemel R, Vandeputte C, De Preter K, De Wilde B, Chicard M, Iddir Y, Schleiermacher G, Ruhen O, Shipley J, Fiocco M, Merks JHM, van Noesel MM, van der Schoot CE, Tytgat GAM, Stutterheim J. Lak NSM, et al. Among authors: tytgat gam. JCO Precis Oncol. 2023 Jan;7:e2200113. doi: 10.1200/PO.22.00113. JCO Precis Oncol. 2023. PMID: 36652664 Free PMC article.
117 results