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Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation.
Holub MN, Wahhab A, Rouse JR, Danner R, McClune MM, Dressler JM, Strle K, Jutras BL, Edelstein AI, Lochhead RB. Holub MN, et al. Among authors: lochhead rb. Res Sq [Preprint]. 2023 Apr 28:rs.3.rs-2842385. doi: 10.21203/rs.3.rs-2842385/v1. Res Sq. 2023. Update in: Arthritis Res Ther. 2024 Mar 27;26(1):77. doi: 10.1186/s13075-024-03293-x PMID: 37162851 Free PMC article. Updated. Preprint.
Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue.
Lochhead RB, Sonderegger FL, Ma Y, Brewster JE, Cornwall D, Maylor-Hagen H, Miller JC, Zachary JF, Weis JH, Weis JJ. Lochhead RB, et al. J Immunol. 2012 Sep 1;189(5):2488-501. doi: 10.4049/jimmunol.1201095. Epub 2012 Jul 30. J Immunol. 2012. PMID: 22851707 Free PMC article.
Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis.
Jutras BL, Lochhead RB, Kloos ZA, Biboy J, Strle K, Booth CJ, Govers SK, Gray J, Schumann P, Vollmer W, Bockenstedt LK, Steere AC, Jacobs-Wagner C. Jutras BL, et al. Among authors: lochhead rb. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13498-13507. doi: 10.1073/pnas.1904170116. Epub 2019 Jun 17. Proc Natl Acad Sci U S A. 2019. PMID: 31209025 Free PMC article.
19 results