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Increased mutation and gene conversion within human segmental duplications.
Vollger MR, Dishuck PC, Harvey WT, DeWitt WS, Guitart X, Goldberg ME, Rozanski AN, Lucas J, Asri M; Human Pangenome Reference Consortium; Munson KM, Lewis AP, Hoekzema K, Logsdon GA, Porubsky D, Paten B, Harris K, Hsieh P, Eichler EE. Vollger MR, et al. Among authors: dewitt ws. Nature. 2023 May;617(7960):325-334. doi: 10.1038/s41586-023-05895-y. Epub 2023 May 10. Nature. 2023. PMID: 37165237 Free PMC article.
Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity.
Montague Z, Lv H, Otwinowski J, DeWitt WS, Isacchini G, Yip GK, Ng WW, Tsang OT, Yuan M, Liu H, Wilson IA, Peiris JSM, Wu NC, Nourmohammad A, Mok CKP. Montague Z, et al. Among authors: dewitt ws. ArXiv [Preprint]. 2021 Apr 6:arXiv:2007.06762v2. ArXiv. 2021. Update in: Cell Rep. 2021 May 25;35(8):109173. doi: 10.1016/j.celrep.2021.109173. PMID: 32699813 Free PMC article. Updated. Preprint.
Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.
Boyle GE, Sitko K, Galloway JG, Haddox HK, Bianchi AH, Dixon A, Wheelock MK, Vandi AJ, Wang ZR, Thomson RES, Garge RK, Rettie AE, Rubin AF, Geck RC, Gillam EMJ, DeWitt WS, Matsen FA 4th, Fowler DM. Boyle GE, et al. Among authors: dewitt ws. Genetics. 2024 Sep 25:iyae156. doi: 10.1093/genetics/iyae156. Online ahead of print. Genetics. 2024. PMID: 39319420
A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility.
Cusanovich DA, Hill AJ, Aghamirzaie D, Daza RM, Pliner HA, Berletch JB, Filippova GN, Huang X, Christiansen L, DeWitt WS, Lee C, Regalado SG, Read DF, Steemers FJ, Disteche CM, Trapnell C, Shendure J. Cusanovich DA, et al. Among authors: dewitt ws. Cell. 2018 Aug 23;174(5):1309-1324.e18. doi: 10.1016/j.cell.2018.06.052. Epub 2018 Aug 2. Cell. 2018. PMID: 30078704 Free PMC article.
A biophysical model of viral escape from polyclonal antibodies.
Yu TC, Thornton ZT, Hannon WW, DeWitt WS, Radford CE, Matsen FA 4th, Bloom JD. Yu TC, et al. Among authors: dewitt ws. Virus Evol. 2022 Dec 12;8(2):veac110. doi: 10.1093/ve/veac110. eCollection 2022. Virus Evol. 2022. PMID: 36582502 Free PMC article.
24 results