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Page 1
Validation of newly derived polygenic risk scores for dementia in a prospective study of older individuals.
Yu C, Ryan J, Orchard SG, Robb C, Woods RL, Wolfe R, Renton AE, Goate AM, Brodtmann A, Shah RC, Chong TT, Sheets K, Kyndt C, Sood A, Storey E, Murray AM, McNeil JJ, Lacaze P. Yu C, et al. Among authors: renton ae. Alzheimers Dement. 2023 Dec;19(12):5333-5342. doi: 10.1002/alz.13113. Epub 2023 May 12. Alzheimers Dement. 2023. PMID: 37177856 Free PMC article.
Polygenic risk score penetrance & recurrence risk in familial Alzheimer disease.
Qiao M, Lee AJ, Reyes-Dumeyer D, Tosto G, Faber K, Goate A, Renton A, Chao M, Boeve B, Cruchaga C, Pericak-Vance M, Haines JL, Rosenberg R, Tsuang D, Sweet RA, Bennett DA, Wilson RS, Foroud T, Mayeux R, Vardarajan BN. Qiao M, et al. Ann Clin Transl Neurol. 2023 May;10(5):744-756. doi: 10.1002/acn3.51757. Epub 2023 Mar 22. Ann Clin Transl Neurol. 2023. PMID: 36946865 Free PMC article.
Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred.
Cochran JN, Acosta-Uribe J, Esposito BT, Madrigal L, Aguillón D, Giraldo MM, Taylor JW, Bradley J, Fulton-Howard B, Andrews SJ, Acosta-Baena N, Alzate D, Garcia GP, Piedrahita F, Lopez HE, Anderson AG, Rodriguez-Nunez I, Roberts K, Dominantly Inherited Alzheimer Network, Absher D, Myers RM, Beecham GW, Reitz C, Rizzardi LF, Fernandez MV, Goate AM, Cruchaga C, Renton AE, Lopera F, Kosik KS. Cochran JN, et al. Among authors: renton ae. Alzheimers Dement. 2023 Sep;19(9):3835-3847. doi: 10.1002/alz.13021. Epub 2023 Mar 23. Alzheimers Dement. 2023. PMID: 36951251 Free PMC article.
Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.
Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR Jr, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, Levey AI, Gordon BA, Schofield PR, Salloway SP, Perrin RJ, McDade E, Levin J, Cruchaga C, Allegri RF, Fox NC, Goate A, Day GS, Koeppe R, Chui HC, Berman S, Mori H, Sanchez-Valle R, Lee JH, Rosa-Neto P, Ruthirakuhan M, Wu CY, Swardfager W, Benzinger TLS, Sohrabi HR, Martins RN, Bateman RJ, Johnson KA, Sperling RA, Greenberg SM, Schultz AP, Chhatwal JP; Dominantly Inherited Alzheimer Network and the Alzheimer’s Disease Neuroimaging Initiative. Shirzadi Z, et al. JAMA Neurol. 2023 Dec 1;80(12):1353-1363. doi: 10.1001/jamaneurol.2023.3618. JAMA Neurol. 2023. PMID: 37843849 Free PMC article.
Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene.
Yu C, Bakshi A, Watts GF, Renton AE, Fulton-Howard B, Goate AM, Natarajan P, Chasman DI, Robman L, Woods RL, Guymer R, Wolfe R, Thao LTP, McNeil JJ, Tonkin AM, Nicholls SJ, Lacaze P. Yu C, et al. Among authors: renton ae. J Am Heart Assoc. 2023 Nov 7;12(21):e031459. doi: 10.1161/JAHA.123.031459. Epub 2023 Nov 6. J Am Heart Assoc. 2023. PMID: 37929782 Free PMC article.
α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.
Levin J, Baiardi S, Quadalti C, Rossi M, Mammana A, Vöglein J, Bernhardt A, Perrin RJ, Jucker M, Preische O, Hofmann A, Höglinger GU, Cairns NJ, Franklin EE, Chrem P, Cruchaga C, Berman SB, Chhatwal JP, Daniels A, Day GS, Ryan NS, Goate AM, Gordon BA, Huey ED, Ibanez L, Karch CM, Lee JH, Llibre-Guerra J, Lopera F, Masters CL, Morris JC, Noble JM, Renton AE, Roh JH, Frosch MP, Keene CD, McLean C, Sanchez-Valle R, Schofield PR, Supnet-Bell C, Xiong C, Giese A, Hansson O, Bateman RJ, McDade E; Dominantly Inherited Alzheimer Network; Parchi P. Levin J, et al. Among authors: renton ae. Alzheimers Dement. 2024 Jun;20(6):4351-4365. doi: 10.1002/alz.13818. Epub 2024 Apr 26. Alzheimers Dement. 2024. PMID: 38666355 Free PMC article.
Social determinants of health but not global genetic ancestry predict dementia prevalence in Latin America.
Llibre-Guerra JJ, Jiang M, Acosta I, Sosa AL, Acosta D, Jimenez-Velasquez IZ, Guerra M, Salas A, Rodriguez Salgado AM, Llibre-Guerra JC, Sánchez ND, Prina M, Renton A, Albanese E, Yokoyama JS, Llibre Rodriguez JJ. Llibre-Guerra JJ, et al. Alzheimers Dement. 2024 Jul;20(7):4828-4840. doi: 10.1002/alz.14041. Epub 2024 Jun 5. Alzheimers Dement. 2024. PMID: 38837526 Free PMC article.
91 results