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Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant.
Wallace MJ, Malhotra N, Mariángelo JIE, Stevens TL, Young LJ, Antwi-Boasiako S, Abdallah D, Takenaka SS, Cavus O, Murphy NP, Han M, Xu X, Mangoni ME, Hund TJ, Roberts JD, Györke S, Mohler PJ, El Refaey M. Wallace MJ, et al. Among authors: han m. J Biol Chem. 2023 Jun;299(6):104818. doi: 10.1016/j.jbc.2023.104818. Epub 2023 May 12. J Biol Chem. 2023. PMID: 37182735 Free PMC article.
Protein Phosphatase 2A Regulates Cardiac Na+ Channels.
El Refaey M, Musa H, Murphy NP, Lubbers ER, Skaf M, Han M, Cavus O, Koenig SN, Wallace MJ, Gratz D, Bradley E, Alsina KM, Wehrens XHT, Hund TJ, Mohler PJ. El Refaey M, et al. Among authors: han m. Circ Res. 2019 Mar;124(5):737-746. doi: 10.1161/CIRCRESAHA.118.314350. Circ Res. 2019. PMID: 30602331 Free PMC article.
Defining new mechanistic roles for αII spectrin in cardiac function.
Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud E, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, Cavus O, Simmons SL, Williams JL, Skaf M, Koenig SN, Janssen PML, Rasband MN, Hund TJ, Mohler PJ. Lubbers ER, et al. Among authors: han m. J Biol Chem. 2019 Jun 14;294(24):9576-9591. doi: 10.1074/jbc.RA119.007714. Epub 2019 May 7. J Biol Chem. 2019. PMID: 31064843 Free PMC article.
Ankyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Roberts JD, Murphy NP, Hamilton RM, Lubbers ER, James CA, Kline CF, Gollob MH, Krahn AD, Sturm AC, Musa H, El-Refaey M, Koenig S, Aneq MÅ, Hoorntje ET, Graw SL, Davies RW, Rafiq MA, Koopmann TT, Aafaqi S, Fatah M, Chiasson DA, Taylor MR, Simmons SL, Han M, van Opbergen CJ, Wold LE, Sinagra G, Mittal K, Tichnell C, Murray B, Codima A, Nazer B, Nguyen DT, Marcus FI, Sobriera N, Lodder EM, van den Berg MP, Spears DA, Robinson JF, Ursell PC, Green AK, Skanes AC, Tang AS, Gardner MJ, Hegele RA, van Veen TA, Wilde AA, Healey JS, Janssen PM, Mestroni L, van Tintelen JP, Calkins H, Judge DP, Hund TJ, Scheinman MM, Mohler PJ. Roberts JD, et al. Among authors: han m. J Clin Invest. 2019 Jul 2;129(8):3171-3184. doi: 10.1172/JCI125538. eCollection 2019 Jul 2. J Clin Invest. 2019. PMID: 31264976 Free PMC article.
Correction: Defining new mechanistic roles for α II spectrin in cardiac function.
Lubbers ER, Murphy NP, Musa H, Huang CY, Gupta R, Price MV, Han M, Daoud GE, Gratz D, El Refaey M, Xu X, Hoeflinger NK, Friel EL, Lancione P, Wallace MJ, Cavus O, Simmons SL, Williams JL, Skaf M, Koenig SN, Janssen PML, Rasband MN, Hund TJ, Mohler PJ. Lubbers ER, et al. Among authors: han m. J Biol Chem. 2019 Oct 18;294(42):15557. doi: 10.1074/jbc.AAC119.011151. J Biol Chem. 2019. PMID: 31628198 Free PMC article. No abstract available.
Giant ankyrin-G regulates cardiac function.
Cavus O, Williams J, Musa H, El Refaey M, Gratz D, Shaheen R, Schwieterman NA, Koenig S, Antwi-Boasiako S, Young LJ, Xu X, Han M, Wold LE, Hund TJ, Mohler PJ, Bradley EA. Cavus O, et al. Among authors: han m. J Biol Chem. 2021 Jan-Jun;296:100507. doi: 10.1016/j.jbc.2021.100507. Epub 2021 Mar 4. J Biol Chem. 2021. PMID: 33675749 Free PMC article.
Altered Expression of Zonula occludens-1 Affects Cardiac Na+ Channels and Increases Susceptibility to Ventricular Arrhythmias.
El Refaey M, Coles S, Musa H, Stevens TL, Wallace MJ, Murphy NP, Antwi-Boasiako S, Young LJ, Manring HR, Curran J, Makara MA, Sas K, Han M, Koenig SN, Skaf M, Kline CF, Janssen PML, Accornero F, Borzok MA, Mohler PJ. El Refaey M, et al. Among authors: han m. Cells. 2022 Feb 14;11(4):665. doi: 10.3390/cells11040665. Cells. 2022. PMID: 35203314 Free PMC article.
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