Medová M - Search Results

1

A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response.

Koch JP, Roth SM, Quintin A, Gavini J, Orlando E, Riedo R, Pozzato C, Hayrapetyan L, Aebersold R, Stroka DM, Aebersold DM, Medo M, Zimmer Y, Medová M. Koch JP, et al. Among authors: medova m. Oncogene. 2023 Jun;42(26):2113-2125. doi: 10.1038/s41388-023-02714-6. Epub 2023 May 15. Oncogene. 2023. PMID: 37188738 Free PMC article.

2

Coupling of mutated Met variants to DNA repair via Abl and Rad51.

Ganapathipillai SS, Medová M, Aebersold DM, Manley PW, Berthou S, Streit B, Blank-Liss W, Greiner RH, Rothen-Rutishauser B, Zimmer Y. Ganapathipillai SS, et al. Among authors: medova m. Cancer Res. 2008 Jul 15;68(14):5769-77. doi: 10.1158/0008-5472.CAN-08-1269. Cancer Res. 2008. PMID: 18632630

3

Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta.

Banz VM, Medová M, Keogh A, Furer C, Zimmer Y, Candinas D, Stroka D. Banz VM, et al. Among authors: medova m. Biochim Biophys Acta. 2009 Oct;1793(10):1597-603. doi: 10.1016/j.bbamcr.2009.08.002. Epub 2009 Aug 12. Biochim Biophys Acta. 2009. PMID: 19682504 Free article.

4

Differential inhibition sensitivities of MET mutants to the small molecule inhibitor SU11274.

Zimmer Y, Vaseva AV, Medová M, Streit B, Blank-Liss W, Greiner RH, Schiering N, Aebersold DM. Zimmer Y, et al. Among authors: medova m. Cancer Lett. 2010 Mar 28;289(2):228-36. doi: 10.1016/j.canlet.2009.08.017. Epub 2009 Sep 23. Cancer Lett. 2010. PMID: 19783361

5

MET inhibition in tumor cells by PHA665752 impairs homologous recombination repair of DNA double strand breaks.

Medová M, Aebersold DM, Zimmer Y. Medová M, et al. Int J Cancer. 2012 Feb 1;130(3):728-34. doi: 10.1002/ijc.26058. Epub 2011 May 9. Int J Cancer. 2012. PMID: 21400509

6

MET Inhibition Results in DNA Breaks and Synergistically Sensitizes Tumor Cells to DNA-Damaging Agents Potentially by Breaching a Damage-Induced Checkpoint Arrest.

Medová M, Aebersold DM, Blank-Liss W, Streit B, Medo M, Aebi S, Zimmer Y. Medová M, et al. Genes Cancer. 2010 Oct;1(10):1053-62. doi: 10.1177/1947601910388030. Genes Cancer. 2010. PMID: 21779429 Free PMC article.

7

Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.

Humbert M, Medová M, Aebersold DM, Blaukat A, Bladt F, Fey MF, Zimmer Y, Tschan MP. Humbert M, et al. Among authors: medova m. Biochem Biophys Res Commun. 2013 Feb 8;431(2):264-9. doi: 10.1016/j.bbrc.2012.12.120. Epub 2013 Jan 9. Biochem Biophys Res Commun. 2013. PMID: 23313490

8

The novel ATP-competitive inhibitor of the MET hepatocyte growth factor receptor EMD1214063 displays inhibitory activity against selected MET-mutated variants.

Medová M, Pochon B, Streit B, Blank-Liss W, Francica P, Stroka D, Keogh A, Aebersold DM, Blaukat A, Bladt F, Zimmer Y. Medová M, et al. Mol Cancer Ther. 2013 Nov;12(11):2415-24. doi: 10.1158/1535-7163.MCT-13-0151. Epub 2013 Sep 23. Mol Cancer Ther. 2013. PMID: 24061647

9

The Molecular Crosstalk between the MET Receptor Tyrosine Kinase and the DNA Damage Response-Biological and Clinical Aspects.

Medová M, Aebersold DM, Zimmer Y. Medová M, et al. Cancers (Basel). 2013 Dec 19;6(1):1-27. doi: 10.3390/cancers6010001. Cancers (Basel). 2013. PMID: 24378750 Free PMC article.

10

Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation.

Leiser D, Pochon B, Blank-Liss W, Francica P, Glück AA, Aebersold DM, Zimmer Y, Medová M. Leiser D, et al. Among authors: medova m. FEBS Lett. 2014 Mar 3;588(5):653-8. doi: 10.1016/j.febslet.2013.12.025. Epub 2014 Jan 17. FEBS Lett. 2014. PMID: 24440350 Free article.

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