Vela JM - Search Results

1

Development of a Novel σ₁ Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.

Morató X, Fernández-Dueñas V, Pérez-Villamor P, Valle-León M, Vela JM, Merlos M, Burgueño J, Ciruela F. Morató X, et al. Among authors: vela jm. ACS Chem Neurosci. 2023 Jun 7;14(11):2201-2207. doi: 10.1021/acschemneuro.3c00206. Epub 2023 May 16. ACS Chem Neurosci. 2023. PMID: 37191585 Free PMC article.

2

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.

Vidal-Torres A, Fernández-Pastor B, García M, Ayet E, Cabot A, Burgueño J, Monroy X, Aubel B, Codony X, Romero L, Pascual R, Serafini MT, Encina G, Almansa C, Zamanillo D, Merlos M, Vela JM. Vidal-Torres A, et al. Among authors: vela jm. Acta Pharm Sin B. 2023 Jan;13(1):82-99. doi: 10.1016/j.apsb.2022.09.018. Epub 2022 Sep 25. Acta Pharm Sin B. 2023. PMID: 36815042 Free PMC article.

3

Discovery of WLB-89462, a New Drug-like and Highly Selective σ₂ Receptor Ligand with Neuroprotective Properties.

Christmann U, Díaz JL, Pascual R, Bordas M, Álvarez I, Monroy X, Porras M, Yeste S, Reinoso RF, Merlos M, Vela JM, Almansa C. Christmann U, et al. Among authors: vela jm. J Med Chem. 2023 Sep 14;66(17):12499-12519. doi: 10.1021/acs.jmedchem.3c01060. Epub 2023 Aug 22. J Med Chem. 2023. PMID: 37607512

4

Resilience to Pain-Related Depression in σ₁ Receptor Knockout Mice Is Associated with the Reversal of Pain-Induced Brain Changes in Affect-Related Genes.

de la Puente B, Zamanillo D, Romero L, Carceller A, Vela JM, Merlos M, Portillo-Salido E. de la Puente B, et al. Among authors: vela jm. ACS Chem Neurosci. 2023 Oct 4;14(19):3714-3725. doi: 10.1021/acschemneuro.3c00502. Epub 2023 Sep 22. ACS Chem Neurosci. 2023. PMID: 37738096

5

WLB-87848, a Selective σ₁ Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity.

Christmann U, Garriga L, Llorente AV, Díaz JL, Pascual R, Bordas M, Dordal A, Porras M, Yeste S, Reinoso RF, Vela JM, Almansa C. Christmann U, et al. Among authors: vela jm. J Med Chem. 2024 Jun 13;67(11):9150-9164. doi: 10.1021/acs.jmedchem.4c00288. Epub 2024 May 16. J Med Chem. 2024. PMID: 38753759

6

Transient Reflexive Pain Responses and Chronic Affective Nonreflexive Pain Responses Associated with Neuroinflammation Processes in Both Spinal and Supraspinal Structures in Spinal Cord-Injured Female Mice.

Castany S, Bagó-Mas A, Vela JM, Verdú E, Bretová K, Svobodová V, Dubový P, Boadas-Vaello P. Castany S, et al. Among authors: vela jm. Int J Mol Sci. 2023 Jan 16;24(2):1761. doi: 10.3390/ijms24021761. Int J Mol Sci. 2023. PMID: 36675275 Free PMC article.

7

Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients.

Grau S, Vela JM, Gurt A, Barceló-Vidal J, Ojeda F, López I, Gómez-García L, Loza MI, Martín-García E, Maldonado R, Monfort J; SIGMA Group. Grau S, et al. Among authors: vela jm. J Infect. 2024 Feb;88(2):187-190. doi: 10.1016/j.jinf.2023.11.008. Epub 2023 Nov 21. J Infect. 2024. PMID: 37992877 Free article. No abstract available.

8

Advanced penile lymphoma: Case report and review of the literature.

Arambulo S, Calle A, Vela JM, Sotelo MJ. Arambulo S, et al. Among authors: vela jm. J Cancer Res Ther. 2023 Apr-Jun;19(3):823-825. doi: 10.4103/jcrt.jcrt_593_21. J Cancer Res Ther. 2023. PMID: 37470619 Free article. Review.

9

Predatory Arthropods Associated with the Invasive Tipu Psyllid, Platycorypha nigrivirga, in Southern Spain.

Del Pino M, Rodríguez MDC, Boyero JR, Vela JM. Del Pino M, et al. Among authors: vela jm. Neotrop Entomol. 2023 Aug;52(4):750-759. doi: 10.1007/s13744-023-01057-x. Epub 2023 Jun 13. Neotrop Entomol. 2023. PMID: 37312011

10

Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models.

Álvarez-Pérez B, Bagó-Mas A, Deulofeu M, Vela JM, Merlos M, Verdú E, Boadas-Vaello P. Álvarez-Pérez B, et al. Among authors: vela jm. Int J Mol Sci. 2022 Oct 8;23(19):11933. doi: 10.3390/ijms231911933. Int J Mol Sci. 2022. PMID: 36233233 Free PMC article.

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