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Inhibitors of Polyphosphate and Neutrophil Extracellular Traps.
Vappala S, Smith SA, Kizhakkedathu JN, Morrissey JH. Vappala S, et al. Among authors: kizhakkedathu jn. Semin Thromb Hemost. 2024 Oct;50(7):970-977. doi: 10.1055/s-0043-1768936. Epub 2023 May 16. Semin Thromb Hemost. 2024. PMID: 37192652 Review.
Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.
Shenoi RA, Kalathottukaren MT, Travers RJ, Lai BF, Creagh AL, Lange D, Yu K, Weinhart M, Chew BH, Du C, Brooks DE, Carter CJ, Morrissey JH, Haynes CA, Kizhakkedathu JN. Shenoi RA, et al. Among authors: kizhakkedathu jn. Sci Transl Med. 2014 Oct 29;6(260):260ra150. doi: 10.1126/scitranslmed.3009427. Epub 2014 Oct 29. Sci Transl Med. 2014. PMID: 25355700
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA.
Kalathottukaren MT, Abraham L, Kapopara PR, Lai BF, Shenoi RA, Rosell FI, Conway EM, Pryzdial EL, Morrissey JH, Haynes CA, Kizhakkedathu JN. Kalathottukaren MT, et al. Among authors: kizhakkedathu jn. Blood. 2017 Mar 9;129(10):1368-1379. doi: 10.1182/blood-2016-10-747915. Epub 2016 Dec 29. Blood. 2017. PMID: 28034889 Free PMC article.
DNASE-MEDIATED DISSOLUTION OF NEUTROPHIL EXTRACELLULAR TRAPS ACCELERATES IN VITRO THROMBIN GENERATION KINETICS IN TRAUMA PATIENTS.
Goswami J, MacArthur TA, Mahony C, Kizhakkedathu JN, Vappala S, Smith S, Morrissey JH, Spears GM, Bailey KR, Dong JF, Kozar RA, Hall N, Johnstone A, Park MS. Goswami J, et al. Among authors: kizhakkedathu jn. Shock. 2022 Sep 1;58(3):217-223. doi: 10.1097/SHK.0000000000001972. Epub 2022 Aug 8. Shock. 2022. PMID: 35959777 Free PMC article.
190 results