Bian J - Search Results

1

Discovery of thiohydantoin based antagonists of androgen receptor with efficient degradation for the treatment of prostate cancer.

Chang X, Zhang D, Qu F, Xie Y, Chen T, Zhang Y, Du Q, Bian J, Li Z, Wang J, Xu X. Chang X, et al. Among authors: bian j. Eur J Med Chem. 2023 Sep 5;257:115490. doi: 10.1016/j.ejmech.2023.115490. Epub 2023 May 18. Eur J Med Chem. 2023. PMID: 37209451

2

Design and synthesis of indoline thiohydantoin derivatives based on enzalutamide as antiproliferative agents against prostate cancer.

Zuo M, Xu X, Xie Z, Ge R, Zhang Z, Li Z, Bian J. Zuo M, et al. Among authors: bian j. Eur J Med Chem. 2017 Jan 5;125:1002-1022. doi: 10.1016/j.ejmech.2016.10.049. Epub 2016 Oct 22. Eur J Med Chem. 2017. PMID: 27810589

3

Affinity-based small fluorescent probe for NAD(P)H:quinone oxidoreductase 1 (NQO1). Design, synthesis and pharmacological evaluation.

Bian J, Li X, Xu L, Wang N, Qian X, You Q, Zhang X. Bian J, et al. Eur J Med Chem. 2017 Feb 15;127:828-839. doi: 10.1016/j.ejmech.2016.10.062. Epub 2016 Nov 1. Eur J Med Chem. 2017. PMID: 27829520

4

Synthesis, evaluation and quantitative structure-activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents.

Bian J, Li T, Weng T, Wang J, Chen Y, Li Z. Bian J, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1012-1016. doi: 10.1016/j.bmcl.2016.12.076. Epub 2017 Jan 5. Bioorg Med Chem Lett. 2017. PMID: 28117202

5

Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile.

Bian J, Li X, Wang N, Wu X, You Q, Zhang X. Bian J, et al. Eur J Med Chem. 2017 Mar 31;129:27-40. doi: 10.1016/j.ejmech.2017.02.004. Epub 2017 Feb 6. Eur J Med Chem. 2017. PMID: 28214631

6

2-Substituted 3,7,8-trimethylnaphtho[1,2-b]furan-4,5-diones as specific L-shaped NQO1-mediated redox modulators for the treatment of non-small cell lung cancer.

Zhang X, Bian J, Li X, Wu X, Dong Y, You Q. Zhang X, et al. Among authors: bian j. Eur J Med Chem. 2017 Sep 29;138:616-629. doi: 10.1016/j.ejmech.2017.06.028. Epub 2017 Jun 15. Eur J Med Chem. 2017. PMID: 28710963

7

Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro.

Wang J, Ge R, Qiu X, Xu X, Wei L, Li Z, Bian J. Wang J, et al. Among authors: bian j. Eur J Med Chem. 2017 Nov 10;140:421-434. doi: 10.1016/j.ejmech.2017.09.046. Epub 2017 Sep 22. Eur J Med Chem. 2017. PMID: 28987604

8

Degradation of Androgen Receptor through Small Molecules for Prostate Cancer.

Ge R, Xu X, Xu P, Li L, Li Z, Bian J. Ge R, et al. Among authors: bian j. Curr Cancer Drug Targets. 2018;18(7):652-667. doi: 10.2174/1568009617666171107103936. Curr Cancer Drug Targets. 2018. PMID: 29110617 Review.

9

Exploring the tetrahydroisoquinoline thiohydantoin scaffold blockade the androgen receptor as potent anti-prostate cancer agents.

Xu X, Ge R, Li L, Wang J, Lu X, Xue S, Chen X, Li Z, Bian J. Xu X, et al. Among authors: bian j. Eur J Med Chem. 2018 Jan 1;143:1325-1344. doi: 10.1016/j.ejmech.2017.10.031. Epub 2017 Oct 14. Eur J Med Chem. 2018. PMID: 29117897

10

Recent discovery of indoleamine-2,3-dioxygenase 1 inhibitors targeting cancer immunotherapy.

Weng T, Qiu X, Wang J, Li Z, Bian J. Weng T, et al. Among authors: bian j. Eur J Med Chem. 2018 Jan 1;143:656-669. doi: 10.1016/j.ejmech.2017.11.088. Epub 2017 Dec 1. Eur J Med Chem. 2018. PMID: 29220788 Review.

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