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IFNα induces CCR5 in CD4+ T-cells, causing its anti- HIV inefficiency and its subsequent pathogenic elevation, partially controlled by anti-HIV therapy.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Song H, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Sajadi MM, Kottilil S, Zagury D, Gallo RC. Le Buanec H, et al. Among authors: song h. Res Sq [Preprint]. 2023 May 11:rs.3.rs-2813616. doi: 10.21203/rs.3.rs-2813616/v1. Res Sq. 2023. Update in: Commun Med (Lond). 2024 Mar 19;4(1):52. doi: 10.1038/s43856-024-00453-7 PMID: 37214795 Free PMC article. Updated. Preprint.
Early Elevated IFNα Identified as the Key Mediator of HIV Pathogenesis and its low level a Hallmark of Elite Controllers.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Song H, Sajadi MM, Kottilil S, Gallo RC, Zagury D. Le Buanec H, et al. Among authors: song h. Res Sq [Preprint]. 2023 May 11:rs.3.rs-2813601. doi: 10.21203/rs.3.rs-2813601/v1. Res Sq. 2023. Update in: Commun Med (Lond). 2024 Mar 19;4(1):53. doi: 10.1038/s43856-024-00454-6 PMID: 37215045 Free PMC article. Updated. Preprint.
Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype.
Song H, Marichannegowda M, Setua S, Bose M, Sanders-Buell E, King D, Zemil M, Wieczorek L, Diaz-Mendez F, Chomont N, Thomas R, Francisco L, Eller LA, Polonis V, Tovanabutra S, Tagaya Y, Michael N, Robb M. Song H, et al. Res Sq [Preprint]. 2023 Sep 25:rs.3.rs-3359209. doi: 10.21203/rs.3.rs-3359209/v1. Res Sq. 2023. Update in: EBioMedicine. 2024 Nov;109:105410. doi: 10.1016/j.ebiom.2024.105410 PMID: 37841838 Free PMC article. Updated. Preprint.
IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Song H, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Sajadi MM, Kottilil S, Zagury D, Gallo RC. Le Buanec H, et al. Among authors: song h. Commun Med (Lond). 2024 Mar 19;4(1):52. doi: 10.1038/s43856-024-00453-7. Commun Med (Lond). 2024. PMID: 38504093 Free PMC article.
Early elevated IFNα is a key mediator of HIV pathogenesis.
Buanec HL, Schiavon V, Merandet M, How-Kit A, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Song H, Sajadi MM, Kottilil S, Gallo RC, Zagury D. Buanec HL, et al. Among authors: song h. Commun Med (Lond). 2024 Mar 19;4(1):53. doi: 10.1038/s43856-024-00454-6. Commun Med (Lond). 2024. PMID: 38504106 Free PMC article.
Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype.
Marichannegowda MH, Setua S, Bose M, Sanders-Buell E, King D, Zemil M, Wieczorek L, Diaz-Mendez F, Chomont N, Thomas R, Francisco L, Eller LA, Polonis VR, Tovanabutra S, Heredia A, Tagaya Y, Michael NL, Robb ML, Song H. Marichannegowda MH, et al. Among authors: song h. EBioMedicine. 2024 Nov;109:105410. doi: 10.1016/j.ebiom.2024.105410. Epub 2024 Oct 19. EBioMedicine. 2024. PMID: 39427414 Free PMC article.
Transmission of highly virulent CXCR4 tropic HIV-1 through the mucosal route in an individual with a wild-type CCR5 genotype.
Marichannegowda MH, Setua S, Bose M, Sanders-Buell E, King D, Zemil M, Wieczorek L, Diaz-Mendez F, Chomont N, Thomas R, Francisco L, Eller LA, Polonis VR, Tovanabutra S, Tagaya Y, Michael NL, Robb ML, Song H. Marichannegowda MH, et al. Among authors: song h. bioRxiv [Preprint]. 2023 Sep 15:2023.09.15.557832. doi: 10.1101/2023.09.15.557832. bioRxiv. 2023. Update in: EBioMedicine. 2024 Nov;109:105410. doi: 10.1016/j.ebiom.2024.105410 PMID: 37745406 Free PMC article. Updated. Preprint.
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