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AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.
Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, George SL, Malik S, Salise J, Morales V, Le Guennec A, Atkinson RA, Marti RM, Matias-Guiu X, Charras G, Conte MR, Elosegui-Artola A, Holt M, Sanz-Moreno V. Crosas-Molist E, et al. Among authors: atkinson ra. Nat Commun. 2023 May 22;14(1):2740. doi: 10.1038/s41467-023-38292-0. Nat Commun. 2023. PMID: 37217519 Free PMC article.
Resonance assignment of human LARP4A La module.
Cruz-Gallardo I, Martino L, Trotta R, De Tito S, Kelly G, Atkinson RA, Randazzo A, Conte MR. Cruz-Gallardo I, et al. Among authors: atkinson ra. Biomol NMR Assign. 2019 Apr;13(1):169-172. doi: 10.1007/s12104-019-09871-4. Epub 2019 Jan 10. Biomol NMR Assign. 2019. PMID: 30632004 Free PMC article.
LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Cruz-Gallardo I, Martino L, Kelly G, Atkinson RA, Trotta R, De Tito S, Coleman P, Ahdash Z, Gu Y, Bui TTT, Conte MR. Cruz-Gallardo I, et al. Among authors: atkinson ra. Nucleic Acids Res. 2019 May 7;47(8):4272-4291. doi: 10.1093/nar/gkz144. Nucleic Acids Res. 2019. PMID: 30820564 Free PMC article.
Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Martino L, Pennell S, Kelly G, Busi B, Brown P, Atkinson RA, Salisbury NJ, Ooi ZH, See KW, Smerdon SJ, Alfano C, Bui TT, Conte MR. Martino L, et al. Among authors: atkinson ra. Nucleic Acids Res. 2015 Jan;43(1):645-60. doi: 10.1093/nar/gku1287. Epub 2014 Dec 8. Nucleic Acids Res. 2015. PMID: 25488812 Free PMC article.
Microbial functional change is linked with clinical outcomes after capsular fecal transplant in cirrhosis.
Bajaj JS, Salzman N, Acharya C, Takei H, Kakiyama G, Fagan A, White MB, Gavis EA, Holtz ML, Hayward M, Nittono H, Hylemon PB, Cox IJ, Williams R, Taylor-Robinson SD, Sterling RK, Matherly SC, Fuchs M, Lee H, Puri P, Stravitz RT, Sanyal AJ, Ajayi L, Le Guennec A, Atkinson RA, Siddiqui MS, Luketic V, Pandak WM, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: atkinson ra. JCI Insight. 2019 Dec 19;4(24):e133410. doi: 10.1172/jci.insight.133410. JCI Insight. 2019. PMID: 31751317 Free PMC article. Clinical Trial.
A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy.
Manzo G, Hind CK, Ferguson PM, Amison RT, Hodgson-Casson AC, Ciazynska KA, Weller BJ, Clarke M, Lam C, Man RCH, Shaughnessy BGO, Clifford M, Bui TT, Drake AF, Atkinson RA, Lam JKW, Pitchford SC, Page CP, Phoenix DA, Lorenz CD, Sutton JM, Mason AJ. Manzo G, et al. Among authors: atkinson ra. Commun Biol. 2020 Nov 27;3(1):697. doi: 10.1038/s42003-020-01420-3. Commun Biol. 2020. PMID: 33247193 Free PMC article.
118 results