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AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.
Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, George SL, Malik S, Salise J, Morales V, Le Guennec A, Atkinson RA, Marti RM, Matias-Guiu X, Charras G, Conte MR, Elosegui-Artola A, Holt M, Sanz-Moreno V. Crosas-Molist E, et al. Among authors: elosegui artola a. Nat Commun. 2023 May 22;14(1):2740. doi: 10.1038/s41467-023-38292-0. Nat Commun. 2023. PMID: 37217519 Free PMC article.
The laminin-keratin link shields the nucleus from mechanical deformation and signalling.
Kechagia Z, Sáez P, Gómez-González M, Canales B, Viswanadha S, Zamarbide M, Andreu I, Koorman T, Beedle AEM, Elosegui-Artola A, Derksen PWB, Trepat X, Arroyo M, Roca-Cusachs P. Kechagia Z, et al. Among authors: elosegui artola a. Nat Mater. 2023 Nov;22(11):1409-1420. doi: 10.1038/s41563-023-01657-3. Epub 2023 Sep 14. Nat Mater. 2023. PMID: 37709930 Free PMC article.
Basal delamination during mouse gastrulation primes pluripotent cells for differentiation.
Sato N, Rosa VS, Makhlouf A, Kretzmer H, Sampath Kumar A, Grosswendt S, Mattei AL, Courbot O, Wolf S, Boulanger J, Langevin F, Wiacek M, Karpinski D, Elosegui-Artola A, Meissner A, Zernicka-Goetz M, Shahbazi MN. Sato N, et al. Among authors: elosegui artola a. Dev Cell. 2024 May 20;59(10):1252-1268.e13. doi: 10.1016/j.devcel.2024.03.008. Epub 2024 Apr 4. Dev Cell. 2024. PMID: 38579720 Free PMC article.
Cell response to extracellular matrix viscous energy dissipation outweighs high-rigidity sensing.
Huerta-López C, Clemente-Manteca A, Velázquez-Carreras D, Espinosa FM, Sanchez JG, Martínez-Del-Pozo Á, García-García M, Martín-Colomo S, Rodríguez-Blanco A, Esteban-González R, Martín-Zamora FM, Gutierrez-Rus LI, Garcia R, Roca-Cusachs P, Elosegui-Artola A, Del Pozo MA, Herrero-Galán E, Sáez P, Plaza GR, Alegre-Cebollada J. Huerta-López C, et al. Among authors: elosegui artola a. Sci Adv. 2024 Nov 15;10(46):eadf9758. doi: 10.1126/sciadv.adf9758. Epub 2024 Nov 15. Sci Adv. 2024. PMID: 39546608 Free PMC article.
Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option.
Uroz M, Stoddard AE, Sutherland BP, Courbot O, Oria R, Li L, Ravasio CR, Ngo MT, Yang J, Tefft JB, Eyckmans J, Han X, Elosegui-Artola A, Weaver VM, Chen CS. Uroz M, et al. Among authors: elosegui artola a. Nat Cell Biol. 2024 Dec;26(12):2144-2153. doi: 10.1038/s41556-024-01532-6. Epub 2024 Oct 24. Nat Cell Biol. 2024. PMID: 39448802
Durable lymph-node expansion is associated with the efficacy of therapeutic vaccination.
Najibi AJ, Lane RS, Sobral MC, Bovone G, Kang S, Freedman BR, Gutierrez Estupinan J, Elosegui-Artola A, Tringides CM, Dellacherie MO, Williams K, Ijaz H, Müller S, Turley SJ, Mooney DJ. Najibi AJ, et al. Among authors: elosegui artola a. Nat Biomed Eng. 2024 Oct;8(10):1226-1242. doi: 10.1038/s41551-024-01209-3. Epub 2024 May 6. Nat Biomed Eng. 2024. PMID: 38710838 Free PMC article.
Matrix viscoelasticity controls spatiotemporal tissue organization.
Elosegui-Artola A, Gupta A, Najibi AJ, Seo BR, Garry R, Tringides CM, de Lázaro I, Darnell M, Gu W, Zhou Q, Weitz DA, Mahadevan L, Mooney DJ. Elosegui-Artola A, et al. Nat Mater. 2023 Jan;22(1):117-127. doi: 10.1038/s41563-022-01400-4. Epub 2022 Dec 1. Nat Mater. 2023. PMID: 36456871 Free PMC article.
Caveolae couple mechanical stress to integrin recycling and activation.
Lolo FN, Pavón DM, Grande-García A, Elosegui-Artola A, Segatori VI, Sánchez S, Trepat X, Roca-Cusachs P, Del Pozo MA. Lolo FN, et al. Among authors: elosegui artola a. Elife. 2022 Oct 20;11:e82348. doi: 10.7554/eLife.82348. Elife. 2022. PMID: 36264062 Free PMC article.
38 results