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Page 1
CD73 controls Myosin II-driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells.
Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L, Lunetto S, Varela A, Orgaz JL, Vilardell F, Olsina JJ, Matias-Guiu X, Sarker D, Biddle A, Balkwill FR, Eyles J, Wilkinson RW, Kocher HM, Calvo F, Wells CM, Sanz-Moreno V. Samain R, et al. Sci Adv. 2023 Oct 20;9(42):eadi0244. doi: 10.1126/sciadv.adi0244. Epub 2023 Oct 18. Sci Adv. 2023. PMID: 37851808 Free PMC article.
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.
Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, George SL, Malik S, Salise J, Morales V, Le Guennec A, Atkinson RA, Marti RM, Matias-Guiu X, Charras G, Conte MR, Elosegui-Artola A, Holt M, Sanz-Moreno V. Crosas-Molist E, et al. Among authors: samain r. Nat Commun. 2023 May 22;14(1):2740. doi: 10.1038/s41467-023-38292-0. Nat Commun. 2023. PMID: 37217519 Free PMC article.
Preclinical to clinical utility of ROCK inhibitors in cancer.
Barcelo J, Samain R, Sanz-Moreno V. Barcelo J, et al. Among authors: samain r. Trends Cancer. 2023 Mar;9(3):250-263. doi: 10.1016/j.trecan.2022.12.001. Epub 2023 Jan 2. Trends Cancer. 2023. PMID: 36599733 Free article. Review.
Periostin- and podoplanin-positive cancer-associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma.
Neuzillet C, Nicolle R, Raffenne J, Tijeras-Raballand A, Brunel A, Astorgues-Xerri L, Vacher S, Arbateraz F, Fanjul M, Hilmi M, Samain R, Klein C, Perraud A, Rebours V, Mathonnet M, Bièche I, Kocher H, Cros J, Bousquet C. Neuzillet C, et al. Among authors: samain r. J Pathol. 2022 Dec;258(4):408-425. doi: 10.1002/path.6011. Epub 2022 Oct 21. J Pathol. 2022. PMID: 36102377 Free PMC article.
Rho GTPase signaling in cancer progression and dissemination.
Crosas-Molist E, Samain R, Kohlhammer L, Orgaz JL, George SL, Maiques O, Barcelo J, Sanz-Moreno V. Crosas-Molist E, et al. Among authors: samain r. Physiol Rev. 2022 Jan 1;102(1):455-510. doi: 10.1152/physrev.00045.2020. Epub 2021 Sep 20. Physiol Rev. 2022. PMID: 34541899 Free article. Review.
Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages.
Samain R, Brunel A, Douché T, Fanjul M, Cassant-Sourdy S, Rochotte J, Cros J, Neuzillet C, Raffenne J, Duluc C, Perraud A, Nigri J, Gigoux V, Bieche I, Ponzo M, Carpentier G, Cascone I, Tomasini R, Schmid HA, Mathonnet M, Nicolle R, Bousquet MP, Martineau Y, Pyronnet S, Jean C, Bousquet C. Samain R, et al. Cell Mol Gastroenterol Hepatol. 2021;11(5):1405-1436. doi: 10.1016/j.jcmgh.2021.01.008. Epub 2021 Jan 20. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33482394 Free PMC article.
FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer.
Zaghdoudi S, Decaup E, Belhabib I, Samain R, Cassant-Sourdy S, Rochotte J, Brunel A, Schlaepfer D, Cros J, Neuzillet C, Strehaiano M, Alard A, Tomasini R, Rajeeve V, Perraud A, Mathonnet M, Pearce OM, Martineau Y, Pyronnet S, Bousquet C, Jean C. Zaghdoudi S, et al. Among authors: samain r. EMBO Mol Med. 2020 Nov 6;12(11):e12010. doi: 10.15252/emmm.202012010. Epub 2020 Oct 7. EMBO Mol Med. 2020. PMID: 33025708 Free PMC article.
eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer.
Müller D, Shin S, Goullet de Rugy T, Samain R, Baer R, Strehaiano M, Masvidal-Sanz L, Guillermet-Guibert J, Jean C, Tsukumo Y, Sonenberg N, Marion F, Guilbaud N, Hoffmann JS, Larsson O, Bousquet C, Pyronnet S, Martineau Y. Müller D, et al. Among authors: samain r. JCI Insight. 2019 Nov 1;4(21):e121951. doi: 10.1172/jci.insight.121951. JCI Insight. 2019. PMID: 31672935 Free PMC article.
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer.
Goehrig D, Nigri J, Samain R, Wu Z, Cappello P, Gabiane G, Zhang X, Zhao Y, Kim IS, Chanal M, Curto R, Hervieu V, de La Fouchardière C, Novelli F, Milani P, Tomasini R, Bousquet C, Bertolino P, Hennino A. Goehrig D, et al. Among authors: samain r. Gut. 2019 Apr;68(4):693-707. doi: 10.1136/gutjnl-2018-317570. Epub 2018 Nov 10. Gut. 2019. PMID: 30415234 Free PMC article.
13 results