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A multi-scale map of protein assemblies in the DNA damage response.
Kratz A, Kim M, Kelly MR, Zheng F, Koczor CA, Li J, Ono K, Qin Y, Churas C, Chen J, Pillich RT, Park J, Modak M, Collier R, Licon K, Pratt D, Sobol RW, Krogan NJ, Ideker T. Kratz A, et al. Among authors: koczor ca. Cell Syst. 2023 Jun 21;14(6):447-463.e8. doi: 10.1016/j.cels.2023.04.007. Epub 2023 May 22. Cell Syst. 2023. PMID: 37220749 Free PMC article.
Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity.
Saville KM, Al-Rahahleh RQ, Siddiqui AH, Andrews ME, Roos WP, Koczor CA, Andrews JF, Hayat F, Migaud ME, Sobol RW. Saville KM, et al. Among authors: koczor ca. DNA Repair (Amst). 2024 Aug;140:103700. doi: 10.1016/j.dnarep.2024.103700. Epub 2024 Jun 4. DNA Repair (Amst). 2024. PMID: 38897003 Free article.
NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells.
Li J, M Saville K, Ibrahim M, Zeng X, McClellan S, Angajala A, Beiser A, Andrews JF, Sun M, Koczor CA, Clark J, Hayat F, Makarov MV, Wilk A, Yates NA, Migaud ME, Sobol RW. Li J, et al. Among authors: koczor ca. NAR Cancer. 2021 Nov 17;3(4):zcab044. doi: 10.1093/narcan/zcab044. eCollection 2021 Dec. NAR Cancer. 2021. PMID: 34806016 Free PMC article.
NAD+-mediated regulation of mammalian base excision repair.
Saville KM, Clark J, Wilk A, Rogers GD, Andrews JF, Koczor CA, Sobol RW. Saville KM, et al. Among authors: koczor ca. DNA Repair (Amst). 2020 Sep;93:102930. doi: 10.1016/j.dnarep.2020.102930. DNA Repair (Amst). 2020. PMID: 33087267 Free PMC article. Review.
26 results