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Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling.
Kejiou NS, Ilan L, Aigner S, Luo E, Tonn T, Ozadam H, Lee M, Cole GB, Rabano I, Rajakulendran N, Yee BA, Najafabadi HS, Moraes TF, Angers S, Yeo GW, Cenik C, Palazzo AF. Kejiou NS, et al. Among authors: najafabadi hs. Nucleic Acids Res. 2023 Jul 7;51(12):6461-6478. doi: 10.1093/nar/gkad440. Nucleic Acids Res. 2023. PMID: 37224531 Free PMC article.
The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation.
Blackburn DM, Sahinyan K, Hernández-Corchado A, Lazure F, Richard V, Raco L, Perron G, Zahedi RP, Borchers CH, Lepper C, Kawabe H, Jahani-Asl A, Najafabadi HS, Soleimani VD. Blackburn DM, et al. Among authors: najafabadi hs. iScience. 2024 Jun 11;27(7):110241. doi: 10.1016/j.isci.2024.110241. eCollection 2024 Jul 19. iScience. 2024. PMID: 39015146 Free PMC article.
GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors.
Jolma A, Hernandez-Corchado A, Yang AWH, Fathi A, Laverty KU, Brechalov A, Razavi R, Albu M, Zheng H; Codebook Consortium; Kulakovskiy IV, Najafabadi HS, Hughes TR. Jolma A, et al. Among authors: najafabadi hs. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.618478. doi: 10.1101/2024.11.11.618478. bioRxiv. 2024. PMID: 39605368 Free PMC article. Preprint.
Extensive binding of uncharacterized human transcription factors to genomic dark matter.
Razavi R, Fathi A, Yellan I, Brechalov A, Laverty KU, Jolma A, Hernandez-Corchado A, Zheng H, Yang AWH, Albu M, Barazandeh M, Hu C, Vorontsov IE, Patel ZM; Codebook Consortium; Kulakovskiy IV, Bucher P, Morris Q, Najafabadi HS, Hughes TR. Razavi R, et al. Among authors: najafabadi hs. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.622123. doi: 10.1101/2024.11.11.622123. bioRxiv. 2024. PMID: 39605320 Free PMC article. Preprint.
Accurate isoform quantification by joint short- and long-read RNA-sequencing.
Apostolides M, Choi B, Navickas A, Saberi A, Soto LM, Goodarzi H, Najafabadi HS. Apostolides M, et al. Among authors: najafabadi hs. bioRxiv [Preprint]. 2024 Jul 13:2024.07.11.603067. doi: 10.1101/2024.07.11.603067. bioRxiv. 2024. PMID: 39026819 Free PMC article. Preprint.
PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.
Rasool D, Burban A, Sharanek A, Madrigal A, Hu J, Yan K, Qu D, Voss AK, Slack RS, Thomas T, Bonni A, Picketts DJ, Soleimani VD, Najafabadi HS, Jahani-Asl A. Rasool D, et al. Among authors: najafabadi hs. EMBO Rep. 2024 Mar;25(3):1256-1281. doi: 10.1038/s44319-024-00082-0. Epub 2024 Mar 1. EMBO Rep. 2024. PMID: 38429579 Free PMC article.
67 results