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Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes.
Ferrins L, Buskes MJ, Kapteyn MM, Engels HN, Enos SE, Lu C, Klug DM, Singh B, Quotadamo A, Bachovchin K, Tear WF, Spaulding AE, Forbes KC, Bag S, Rivers M, LeBlanc C, Burchfield E, Armand JR, Diaz-Gonzalez R, Ceballos-Perez G, García-Hernández R, Pérez-Moreno G, Bosch-Navarrete C, Ruiz-Pérez LM, Gamarro F, González-Pacanowska D, Navarro M, Mensa-Wilmot K, Pollastri MP, Kyle DE, Rice CA. Ferrins L, et al. Front Microbiol. 2023 May 10;14:1149145. doi: 10.3389/fmicb.2023.1149145. eCollection 2023. Front Microbiol. 2023. PMID: 37234530 Free PMC article.
Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi.
Varghese S, Rahmani R, Russell S, Deora GS, Ferrins L, Toynton A, Jones A, Sykes M, Kessler A, Eufrásio A, Cordeiro AT, Sherman J, Rodriguez A, Avery VM, Piggott MJ, Baell JB. Varghese S, et al. Among authors: ferrins l. ACS Med Chem Lett. 2019 Sep 9;11(3):278-285. doi: 10.1021/acsmedchemlett.9b00218. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184957 Free PMC article.
A Diverse View of Science to Catalyse Change.
Urbina-Blanco CA, Jilani SZ, Speight IR, Bojdys MJ, Friščić T, Stoddart JF, Nelson TL, Mack J, Robinson RAS, Waddell EA, Lutkenhaus JL, Godfrey M, Abboud MI, Aderinto SO, Aderohunmu D, Bibič L, Borges J, Dong VM, Ferrins L, Fung FM, John T, Lim FPL, Masters SL, Mambwe D, Thordarson P, Titirici MM, Tormet-González GD, Unterlass MM, Wadle A, Yam VW, Yang YW. Urbina-Blanco CA, et al. Among authors: ferrins l. Angew Chem Int Ed Engl. 2020 Oct 12;59(42):18306-18310. doi: 10.1002/anie.202009834. Epub 2020 Aug 17. Angew Chem Int Ed Engl. 2020. PMID: 33448562 Free PMC article. Review.
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.
Jansen J, Reimer KC, Nagai JS, Varghese FS, Overheul GJ, de Beer M, Roverts R, Daviran D, Fermin LAS, Willemsen B, Beukenboom M, Djudjaj S, von Stillfried S, van Eijk LE, Mastik M, Bulthuis M, Dunnen WD, van Goor H, Hillebrands JL, Triana SH, Alexandrov T, Timm MC, van den Berge BT, van den Broek M, Nlandu Q, Heijnert J, Bindels EMJ, Hoogenboezem RM, Mooren F, Kuppe C, Miesen P, Grünberg K, Ijzermans T, Steenbergen EJ, Czogalla J, Schreuder MF, Sommerdijk N, Akiva A, Boor P, Puelles VG, Floege J, Huber TB; COVID Moonshot consortium; van Rij RP, Costa IG, Schneider RK, Smeets B, Kramann R. Jansen J, et al. Cell Stem Cell. 2022 Feb 3;29(2):217-231.e8. doi: 10.1016/j.stem.2021.12.010. Epub 2021 Dec 25. Cell Stem Cell. 2022. PMID: 35032430 Free PMC article.
Anilinoquinoline based inhibitors of trypanosomatid proliferation.
Ferrins L, Sharma A, Thomas SM, Mehta N, Erath J, Tanghe S, Leed SE, Rodriguez A, Mensa-Wilmot K, Sciotti RJ, Gillingwater K, Pollastri MP. Ferrins L, et al. PLoS Negl Trop Dis. 2018 Nov 26;12(11):e0006834. doi: 10.1371/journal.pntd.0006834. eCollection 2018 Nov. PLoS Negl Trop Dis. 2018. PMID: 30475800 Free PMC article.
42 results