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GIP receptor agonism blocks chemotherapy-induced nausea and vomiting.
Borner T, Reiner BC, Crist RC, Furst CD, Doebley SA, Halas JG, Ai M, Samms RJ, De Jonghe BC, Hayes MR. Borner T, et al. Among authors: furst cd. Mol Metab. 2023 Jul;73:101743. doi: 10.1016/j.molmet.2023.101743. Epub 2023 May 26. Mol Metab. 2023. PMID: 37245848 Free PMC article.
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects.
Asker M, Krieger JP, Liles A, Tinsley IC, Borner T, Maric I, Doebley S, Furst CD, Börchers S, Longo F, Bhat YR, De Jonghe BC, Hayes MR, Doyle RP, Skibicka KP. Asker M, et al. Among authors: furst cd. Diabetes Obes Metab. 2023 Mar;25(3):856-877. doi: 10.1111/dom.14937. Epub 2023 Jan 9. Diabetes Obes Metab. 2023. PMID: 36495318 Free PMC article.