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Page 1
Circulating levels of proglucagon-derived peptides are differentially regulated by the glucagon-like peptide-1 agonist liraglutide and the centrally acting naltrexone/bupropion and can predict future weight loss and metabolic improvements: A 6-month long interventional study.
Stefanakis K, Kokkinos A, Argyrakopoulou G, Konstantinidou SK, Simati S, Kouvari M, Kumar A, Kalra B, Kumar M, Bontozoglou N, Kyriakopoulou K, Mantzoros CS. Stefanakis K, et al. Among authors: simati s. Diabetes Obes Metab. 2023 Sep;25(9):2561-2574. doi: 10.1111/dom.15141. Epub 2023 May 29. Diabetes Obes Metab. 2023. PMID: 37246799 Free PMC article.
Pleurotus eryngii improves postprandial glycaemia, hunger and fullness perception, and enhances ghrelin suppression in people with metabolically unhealthy obesity.
Kleftaki SA, Simati S, Amerikanou C, Gioxari A, Tzavara C, Zervakis GI, Kalogeropoulos N, Kokkinos A, Kaliora AC. Kleftaki SA, et al. Among authors: simati s. Pharmacol Res. 2022 Jan;175:105979. doi: 10.1016/j.phrs.2021.105979. Epub 2021 Nov 16. Pharmacol Res. 2022. PMID: 34798266 Clinical Trial.
Obesity Paradox: Fact or Fiction?
Simati S, Kokkinos A, Dalamaga M, Argyrakopoulou G. Simati S, et al. Curr Obes Rep. 2023 Jun;12(2):75-85. doi: 10.1007/s13679-023-00497-1. Epub 2023 Feb 20. Curr Obes Rep. 2023. PMID: 36808566 Review.
Circulating levels of all proglucagon-derived peptides are differentially regulated postprandially by obesity status and in response to high-fat meals vs. high-carbohydrate meals.
Stefanakis K, Kokkinos A, Simati S, Argyrakopoulou G, Konstantinidou SK, Kouvari M, Kumar A, Kalra B, Mantzoros CS. Stefanakis K, et al. Among authors: simati s. Clin Nutr. 2023 Aug;42(8):1369-1378. doi: 10.1016/j.clnu.2023.06.026. Epub 2023 Jun 28. Clin Nutr. 2023. PMID: 37418844
Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity.
Boutari C, Stefanakis K, Simati S, Guatibonza-García V, Valenzuela-Vallejo L, Anastasiou IA, Connelly MA, Kokkinos A, Mantzoros CS. Boutari C, et al. Among authors: simati s. Cardiovasc Diabetol. 2024 May 18;23(1):174. doi: 10.1186/s12933-024-02264-5. Cardiovasc Diabetol. 2024. PMID: 38762719 Free PMC article.
Bariatric surgery, through beneficial effects on underlying mechanisms, improves cardiorenal and liver metabolic risk over an average of ten years of observation: A longitudinal and a case-control study.
Kokkinos A, Tsilingiris D, Simati S, Stefanakis K, Angelidi AM, Tentolouris N, Anastasiou IA, Connelly MA, Alexandrou A, Mantzoros CS. Kokkinos A, et al. Among authors: simati s. Metabolism. 2024 Mar;152:155773. doi: 10.1016/j.metabol.2023.155773. Epub 2024 Jan 3. Metabolism. 2024. PMID: 38181882