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Vinculin Y822 is an important determinant of ligand binding.
J Cell Sci. 2023 Jun 15;136(12):jcs260104. doi: 10.1242/jcs.260104. Epub 2023 Jun 14.
J Cell Sci. 2023.
PMID: 37248996
Free PMC article.
SHP-2 is activated in response to force on E-cadherin and dephosphorylates vinculin Y822.
Campbell H, Heidema C, Pilarczyk DG, DeMali KA.
Campbell H, et al. Among authors: heidema c.
J Cell Sci. 2018 Dec 14;131(24):jcs216648. doi: 10.1242/jcs.216648.
J Cell Sci. 2018.
PMID: 30478196
Free PMC article.
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Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK.
Bays JL, Campbell HK, Heidema C, Sebbagh M, DeMali KA.
Bays JL, et al. Among authors: heidema c.
Nat Cell Biol. 2017 Jun;19(6):724-731. doi: 10.1038/ncb3537. Epub 2017 May 29.
Nat Cell Biol. 2017.
PMID: 28553939
Free PMC article.
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