Silasi R - Search Results

1

Anti-miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response.

Dragomir MP, Fuentes-Mattei E, Winkle M, Okubo K, Bayraktar R, Knutsen E, Qdaisat A, Chen M, Li Y, Shimizu M, Pang L, Liu K, Liu X, Anfossi S, Zhang H, Koch I, Tran AM, Mohapatra S, Ton A, Kaplan M, Anderson MW, Rothfuss SJ, Silasi R, Keshari RS, Ferracin M, Ivan C, Rodriguez-Aguayo C, Lopez-Berestein G, Georgescu C, Banerjee PP, Basar R, Li Z, Horst D, Vasilescu C, Bertilaccio MTS, Rezvani K, Lupu F, Yeung SC, Calin GA. Dragomir MP, et al. Among authors: silasi r. J Clin Invest. 2023 Jul 17;133(14):e158348. doi: 10.1172/JCI158348. J Clin Invest. 2023. PMID: 37261908 Free PMC article.

2

Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis.

Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F. Keshari RS, et al. Among authors: silasi r. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6390-E6399. doi: 10.1073/pnas.1706818114. Epub 2017 Jul 18. Proc Natl Acad Sci U S A. 2017. PMID: 28720697 Free PMC article.

3

In vivo-generated thrombin and plasmin do not activate the complement system in baboons.

Keshari RS, Silasi R, Lupu C, Taylor FB Jr, Lupu F. Keshari RS, et al. Among authors: silasi r. Blood. 2017 Dec 14;130(24):2678-2681. doi: 10.1182/blood-2017-06-788216. Epub 2017 Oct 11. Blood. 2017. PMID: 29021229 Free PMC article.

4

Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways.

Popescu NI, Silasi R, Keshari RS, Girton A, Burgett T, Zeerleder SS, Gailani D, Gruber A, Lupu F, Coggeshall KM. Popescu NI, et al. Among authors: silasi r. Blood. 2018 Aug 23;132(8):849-860. doi: 10.1182/blood-2017-10-813618. Epub 2018 Jun 19. Blood. 2018. PMID: 29921614 Free PMC article.

5

Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function.

Patel MM, Behar AR, Silasi R, Regmi G, Sansam CL, Keshari RS, Lupu F, Lupu C. Patel MM, et al. Among authors: silasi r. J Am Heart Assoc. 2018 Nov 20;7(22):e010690. doi: 10.1161/JAHA.118.010690. J Am Heart Assoc. 2018. PMID: 30571485 Free PMC article.

6

Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death.

Silasi R, Keshari RS, Lupu C, Van Rensburg WJ, Chaaban H, Regmi G, Shamanaev A, Shatzel JJ, Puy C, Lorentz CU, Tucker EI, Gailani D, Gruber A, McCarty OJT, Lupu F. Silasi R, et al. Blood Adv. 2019 Feb 26;3(4):658-669. doi: 10.1182/bloodadvances.2018029983. Blood Adv. 2019. PMID: 30808684 Free PMC article.

7

Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of Escherichia coli sepsis.

Keshari RS, Silasi R, Popescu NI, Georgescu C, Chaaban H, Lupu C, McCarty OJT, Esmon CT, Lupu F. Keshari RS, et al. Among authors: silasi r. J Thromb Haemost. 2020 Jan;18(1):180-190. doi: 10.1111/jth.14642. Epub 2019 Oct 16. J Thromb Haemost. 2020. PMID: 31549765 Free PMC article.

8

Neutrophil extracellular trap inhibition increases inflammation, bacteraemia and mortality in murine necrotizing enterocolitis.

Chaaban H, Burge K, Eckert J, Keshari RS, Silasi R, Lupu C, Warner B, Escobedo M, Caplan M, Lupu F. Chaaban H, et al. Among authors: silasi r. J Cell Mol Med. 2021 Dec;25(23):10814-10824. doi: 10.1111/jcmm.15338. Epub 2020 Jun 8. J Cell Mol Med. 2021. PMID: 32515131 Free PMC article.

9

CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis.

Keshari RS, Silasi R, Popescu NI, Regmi G, Chaaban H, Lambris JD, Lupu C, Mollnes TE, Lupu F. Keshari RS, et al. Among authors: silasi r. J Thromb Haemost. 2021 Feb;19(2):429-443. doi: 10.1111/jth.15162. Epub 2020 Dec 3. J Thromb Haemost. 2021. PMID: 33174372 Free PMC article.

10

Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus.

Silasi R, Keshari RS, Regmi G, Lupu C, Georgescu C, Simmons JH, Wallisch M, Kohs TCL, Shatzel JJ, Olson SR, Lorentz CU, Puy C, Tucker EI, Gailani D, Strickland S, Gruber A, McCarty OJT, Lupu F. Silasi R, et al. Blood. 2021 Jul 15;138(2):178-189. doi: 10.1182/blood.2020009345. Blood. 2021. PMID: 33598692 Free PMC article.

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