Gudgeon N - Search Results

1

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma.

Gudgeon N, Giles H, Bishop EL, Fulton-Ward T, Escribano-Gonzalez C, Munford H, James-Bott A, Foster K, Karim F, Jayawardana D, Mahmood A, Cribbs AP, Tennant DA, Basu S, Pratt G, Dimeloe S. Gudgeon N, et al. Blood Adv. 2023 Oct 24;7(20):6035-6047. doi: 10.1182/bloodadvances.2023009890. Blood Adv. 2023. PMID: 37276076 Free PMC article.

2

Control of T Cell Metabolism by Cytokines and Hormones.

Bishop EL, Gudgeon N, Dimeloe S. Bishop EL, et al. Among authors: gudgeon n. Front Immunol. 2021 Apr 13;12:653605. doi: 10.3389/fimmu.2021.653605. eCollection 2021. Front Immunol. 2021. PMID: 33927722 Free PMC article. Review.

3

1,25-Dihydroxyvitamin D3 suppresses CD4⁺ T-cell effector functionality by inhibition of glycolysis.

Bishop EL, Gudgeon NH, Mackie GM, Chauss D, Roberts J, Tennant DA, Maslowski KM, Afzali B, Hewison M, Dimeloe S. Bishop EL, et al. Among authors: gudgeon nh. Immunology. 2022 Jul;166(3):299-309. doi: 10.1111/imm.13472. Epub 2022 Mar 28. Immunology. 2022. PMID: 35322416 Free PMC article.

4

Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation.

Gudgeon N, Munford H, Bishop EL, Hill J, Fulton-Ward T, Bending D, Roberts J, Tennant DA, Dimeloe S. Gudgeon N, et al. Cell Rep. 2022 Aug 16;40(7):111193. doi: 10.1016/j.celrep.2022.111193. Cell Rep. 2022. PMID: 35977513 Free PMC article.

5

TNF-α signals through ITK-Akt-mTOR to drive CD4⁺ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.

Bishop EL, Gudgeon N, Fulton-Ward T, Stavrou V, Roberts J, Boufersaoui A, Tennant DA, Hewison M, Raza K, Dimeloe S. Bishop EL, et al. Among authors: gudgeon n. Sci Signal. 2024 Apr 23;17(833):eadg5678. doi: 10.1126/scisignal.adg5678. Epub 2024 Apr 23. Sci Signal. 2024. PMID: 38652761

6

Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential.

Dunne PJ, Faint JM, Gudgeon NH, Fletcher JM, Plunkett FJ, Soares MV, Hislop AD, Annels NE, Rickinson AB, Salmon M, Akbar AN. Dunne PJ, et al. Among authors: gudgeon nh. Blood. 2002 Aug 1;100(3):933-40. doi: 10.1182/blood-2002-01-0160. Blood. 2002. PMID: 12130505 Free article.

7

CD4+ T-cell clones recognizing human lymphoma-associated antigens: generation by in vitro stimulation with autologous Epstein-Barr virus-transformed B cells.

Long HM, Zuo J, Leese AM, Gudgeon NH, Jia H, Taylor GS, Rickinson AB. Long HM, et al. Among authors: gudgeon nh. Blood. 2009 Jul 23;114(4):807-15. doi: 10.1182/blood-2008-12-194043. Epub 2009 May 14. Blood. 2009. PMID: 19443664 Free article.

8

EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function.

Hislop AD, Gudgeon NH, Callan MF, Fazou C, Hasegawa H, Salmon M, Rickinson AB. Hislop AD, et al. Among authors: gudgeon nh. J Immunol. 2001 Aug 15;167(4):2019-29. doi: 10.4049/jimmunol.167.4.2019. J Immunol. 2001. PMID: 11489984

9

Regression of Epstein-Barr virus-induced B-cell transformation in vitro involves virus-specific CD8+ T cells as the principal effectors and a novel CD4+ T-cell reactivity.

Gudgeon NH, Taylor GS, Long HM, Haigh TA, Rickinson AB. Gudgeon NH, et al. J Virol. 2005 May;79(9):5477-88. doi: 10.1128/JVI.79.9.5477-5488.2005. J Virol. 2005. PMID: 15827162 Free PMC article.

10

Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection.

Khan N, Hislop A, Gudgeon N, Cobbold M, Khanna R, Nayak L, Rickinson AB, Moss PA. Khan N, et al. Among authors: gudgeon n. J Immunol. 2004 Dec 15;173(12):7481-9. doi: 10.4049/jimmunol.173.12.7481. J Immunol. 2004. PMID: 15585874

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