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The German Network for Personalized Medicine to enhance patient care and translational research.
Illert AL, Stenzinger A, Bitzer M, Horak P, Gaidzik VI, Möller Y, Beha J, Öner Ö, Schmitt F, Laßmann S, Ossowski S, Schaaf CP, Hallek M, Brümmendorf TH, Albers P, Fehm T, Brossart P, Glimm H, Schadendorf D, Bleckmann A, Brandts CH, Esposito I, Mack E, Peters C, Bokemeyer C, Fröhling S, Kindler T, Algül H, Heinemann V, Döhner H, Bargou R, Ellenrieder V, Hillemanns P, Lordick F, Hochhaus A, Beckmann MW, Pukrop T, Trepel M, Sundmacher L, Wesselmann S, Nettekoven G, Kohlhuber F, Heinze O, Budczies J, Werner M, Nikolaou K, Beer AJ, Tabatabai G, Weichert W, Keilholz U, Boerries M, Kohlbacher O, Duyster J, Thimme R, Seufferlein T, Schirmacher P, Malek NP. Illert AL, et al. Among authors: esposito i. Nat Med. 2023 Jun;29(6):1298-1301. doi: 10.1038/s41591-023-02354-z. Nat Med. 2023. PMID: 37280276 No abstract available.
Evaluation of the effectiveness of a nationwide precision medicine program for patients with advanced non-small cell lung cancer in Germany: a historical cohort analysis.
Kästner A, Kron A, van den Berg N, Moon K, Scheffler M, Schillinger G, Pelusi N, Hartmann N, Rieke DT, Stephan-Falkenau S, Schuler M, Wermke M, Weichert W, Klauschen F, Haller F, Hummel HD, Sebastian M, Gattenlöhner S, Bokemeyer C, Esposito I, Jakobs F, von Kalle C, Büttner R, Wolf J, Hoffmann W. Kästner A, et al. Among authors: esposito i. Lancet Reg Health Eur. 2023 Nov 22;36:100788. doi: 10.1016/j.lanepe.2023.100788. eCollection 2024 Jan. Lancet Reg Health Eur. 2023. PMID: 38034041 Free PMC article.
Semaphorin-3A regulates liver sinusoidal endothelial cell porosity and promotes hepatic steatosis.
Eberhard D, Balkenhol S, Köster A, Follert P, Upschulte E, Ostermann P, Kirschner P, Uhlemeyer C, Charnay I, Preuss C, Trenkamp S, Belgardt BF, Dickscheid T, Esposito I, Roden M, Lammert E. Eberhard D, et al. Among authors: esposito i. Nat Cardiovasc Res. 2024 Jun;3(6):734-753. doi: 10.1038/s44161-024-00487-z. Epub 2024 Jun 14. Nat Cardiovasc Res. 2024. PMID: 39196233 Free PMC article.
A clinically compatible in vitro drug-screening platform identifies therapeutic vulnerabilities in primary cultures of brain metastases.
Jeising S, Nickel AC, Trübel J, Felsberg J, Picard D, Leprivier G, Wolter M, Huynh MK, Olivera MB, Kaulich K, Häberle L, Esposito I, Klau GW, Steinmann J, Beez T, Rapp M, Sabel M, Dietrich S, Remke M, Cornelius JF, Reifenberger G, Qin N. Jeising S, et al. Among authors: esposito i. J Neurooncol. 2024 Sep;169(3):613-623. doi: 10.1007/s11060-024-04763-7. Epub 2024 Jul 10. J Neurooncol. 2024. PMID: 38985431 Free PMC article.
New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance.
Klein-Rodewald T, Micklich K, Sanz-Moreno A, Tost M, Calzada-Wack J, Adler T, Klaften M, Sabrautzki S, Aigner B, Kraiger M, Gailus-Durner V, Fuchs H; German Mouse Clinic Consortium; Gründer A, Pahl H, Wolf E, Hrabe de Angelis M, Rathkolb B. Klein-Rodewald T, et al. Sci Rep. 2022 Nov 17;12(1):19793. doi: 10.1038/s41598-022-23218-5. Sci Rep. 2022. PMID: 36396684 Free PMC article.
Loss of mitochondrial adaptation associates with deterioration of mitochondrial turnover and structure in metabolic dysfunction-associated steatotic liver disease.
Sarabhai T, Kahl S, Gancheva S, Mastrototaro L, Dewidar B, Pesta D, Ratter-Rieck JM, Bobrov P, Jeruschke K, Esposito I, Schlensak M, Roden M. Sarabhai T, et al. Among authors: esposito i. Metabolism. 2024 Feb;151:155762. doi: 10.1016/j.metabol.2023.155762. Epub 2023 Dec 19. Metabolism. 2024. Retraction in: Metabolism. 2024 Dec 24;164:156107. doi: 10.1016/j.metabol.2024.156107 PMID: 38122893 Retracted.
Dysglycemia and liver lipid content determine the relationship of insulin resistance with hepatic OXPHOS capacity in obesity.
Kahl S, Straßburger K, Pacini G, Trinks N, Pafili K, Mastrototaro L, Dewidar B, Sarabhai T, Trenkamp S, Esposito I, Schlensak M, Granderath FA, Roden M. Kahl S, et al. Among authors: esposito i. J Hepatol. 2024 Aug 31:S0168-8278(24)02490-5. doi: 10.1016/j.jhep.2024.08.012. Online ahead of print. J Hepatol. 2024. PMID: 39218222 Free article.
520 results