Villa A - Search Results

1

Generation of a novel fully human non-superagonistic anti-CD28 antibody with efficient and safe T-cell co-stimulation properties.

Elsayed A, Pellegrino C, Plüss L, Peissert F, Benz R, Ulrich F, Thorhallsdottir G, Plaza SD, Villa A, Mock J, Puca E, De Luca R, Manz MG, Halin C, Neri D. Elsayed A, et al. Among authors: villa a. MAbs. 2023 Jan-Dec;15(1):2220839. doi: 10.1080/19420862.2023.2220839. MAbs. 2023. PMID: 37288872 Free PMC article.

2

Novel human monoclonal antibodies specific to the alternatively spliced domain D of Tenascin C efficiently target tumors in vivo.

Nadal L, Corbellari R, Villa A, Weiss T, Weller M, Neri D, De Luca R. Nadal L, et al. Among authors: villa a. MAbs. 2020 Jan-Dec;12(1):1836713. doi: 10.1080/19420862.2020.1836713. MAbs. 2020. PMID: 33136526 Free PMC article.

3

Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen.

Plüss L, Peissert F, Elsayed A, Rotta G, Römer J, Dakhel Plaza S, Villa A, Puca E, De Luca R, Oxenius A, Neri D. Plüss L, et al. Among authors: villa a. MAbs. 2023 Jan-Dec;15(1):2217964. doi: 10.1080/19420862.2023.2217964. MAbs. 2023. PMID: 37243574 Free PMC article.

4

A novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin.

Villa A, Lovato V, Bujak E, Wulhfard S, Pasche N, Neri D. Villa A, et al. MAbs. 2011 May-Jun;3(3):264-72. doi: 10.4161/mabs.3.3.15616. Epub 2011 May 1. MAbs. 2011. PMID: 21487243 Free PMC article.

5

Selection of a PD-1 blocking antibody from a novel fully human phage display library.

Peissert F, Plüss L, Giudice AM, Ongaro T, Villa A, Elsayed A, Nadal L, Dakhel Plaza S, Scietti L, Puca E, De Luca R, Forneris F, Neri D. Peissert F, et al. Among authors: villa a. Protein Sci. 2022 Dec;31(12):e4486. doi: 10.1002/pro.4486. Protein Sci. 2022. PMID: 36317676 Free PMC article.

6

A novel anti-cancer L19-interleukin-12 fusion protein with an optimized peptide linker efficiently localizes in vivo at the site of tumors.

Ongaro T, Matasci M, Cazzamalli S, Gouyou B, De Luca R, Neri D, Villa A. Ongaro T, et al. Among authors: villa a. J Biotechnol. 2019 Feb 10;291:17-25. doi: 10.1016/j.jbiotec.2018.12.004. Epub 2018 Dec 23. J Biotechnol. 2019. PMID: 30586544

7

A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Carcinomas.

De Luca R, Gouyou B, Ongaro T, Villa A, Ziffels B, Sannino A, Buttinoni G, Galeazzi S, Mazzacuva M, Neri D. De Luca R, et al. Among authors: villa a. Front Oncol. 2019 Nov 13;9:1228. doi: 10.3389/fonc.2019.01228. eCollection 2019. Front Oncol. 2019. PMID: 31799191 Free PMC article.

8

The immunocytokine L19-TNF eradicates sarcomas in combination with chemotherapy agents or with immune check-point inhibitors.

Corbellari R, Nadal L, Villa A, Neri D, De Luca R. Corbellari R, et al. Among authors: villa a. Anticancer Drugs. 2020 Sep;31(8):799-805. doi: 10.1097/CAD.0000000000000938. Anticancer Drugs. 2020. PMID: 32304410

9

An engineered 4-1BBL fusion protein with "activity on demand".

Mock J, Stringhini M, Villa A, Weller M, Weiss T, Neri D. Mock J, et al. Among authors: villa a. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31780-31788. doi: 10.1073/pnas.2013615117. Epub 2020 Nov 25. Proc Natl Acad Sci U S A. 2020. PMID: 33239441 Free PMC article.

10

Immunotherapy with Immunocytokines and PD-1 Blockade Enhances the Anticancer Activity of Small Molecule-Drug Conjugates Targeting Carbonic Anhydrase IX.

Millul J, Krudewig C, Zana A, Dakhel Plaza S, Puca E, Villa A, Neri D, Cazzamalli S. Millul J, et al. Among authors: villa a. Mol Cancer Ther. 2021 Mar;20(3):512-522. doi: 10.1158/1535-7163.MCT-20-0361. Epub 2020 Dec 22. Mol Cancer Ther. 2021. PMID: 33443104 Free PMC article.

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