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Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles.
Hunter MR, Cui L, Porebski BT, Pereira S, Sonzini S, Odunze U, Iyer P, Engkvist O, Lloyd RL, Peel S, Sabirsh A, Ross-Thriepland D, Jones AT, Desai AS. Hunter MR, et al. Among authors: engkvist o. Small Methods. 2023 Sep;7(9):e2201695. doi: 10.1002/smtd.202201695. Epub 2023 Jun 14. Small Methods. 2023. PMID: 37317010 Free PMC article.
The European Lead Factory: Results from a decade of collaborative, public-private, drug discovery programs.
van Vlijmen H, Pannifer AD, Cochrane P, Basting D, Li VM, Engkvist O, Ortholand JY, Wagener M, Duffy J, Finsinger D, Davis J, van Helden SP, de Vlieger JSB; European Lead Factory Consortium. van Vlijmen H, et al. Among authors: engkvist o. Drug Discov Today. 2024 Mar;29(3):103886. doi: 10.1016/j.drudis.2024.103886. Epub 2024 Jan 18. Drug Discov Today. 2024. PMID: 38244673 Free article. Review.
Collaborative virtual screening to elaborate an imidazo[1,2-a]pyridine hit series for visceral leishmaniasis.
Akao Y, Canan S, Cao Y, Condroski K, Engkvist O, Itono S, Kaki R, Kimura C, Kogej T, Nagaoka K, Naito A, Nakai H, Pairaudeau G, Radu C, Roberts I, Shimada M, Shum D, Watanabe NA, Xie H, Yonezawa S, Yoshida O, Yoshida R, Mowbray C, Perry B. Akao Y, et al. Among authors: engkvist o. RSC Med Chem. 2021 Jan 21;12(3):384-393. doi: 10.1039/d0md00353k. RSC Med Chem. 2021. PMID: 34041487 Free PMC article.
Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway.
Fan J, Zhao RQ, Parro C, Zhao W, Chou HY, Robert J, Deeb TZ, Raynoschek C, Barichievy S, Engkvist O, Maresca M, Hicks R, Meuller J, Moss SJ, Brandon NJ, Wood MW, Kulic I, Wellington CL. Fan J, et al. Among authors: engkvist o. J Lipid Res. 2018 May;59(5):830-842. doi: 10.1194/jlr.M081851. Epub 2018 Mar 21. J Lipid Res. 2018. PMID: 29563219 Free PMC article.
168 results