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Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs.
Beattie AT, Dunkelmann DL, Chin JW. Beattie AT, et al. Among authors: dunkelmann dl. Nat Chem. 2023 Jul;15(7):948-959. doi: 10.1038/s41557-023-01232-y. Epub 2023 Jun 15. Nat Chem. 2023. PMID: 37322102 Free PMC article.
Total synthesis of Escherichia coli with a recoded genome.
Fredens J, Wang K, de la Torre D, Funke LFH, Robertson WE, Christova Y, Chia T, Schmied WH, Dunkelmann DL, Beránek V, Uttamapinant C, Llamazares AG, Elliott TS, Chin JW. Fredens J, et al. Among authors: dunkelmann dl. Nature. 2019 May;569(7757):514-518. doi: 10.1038/s41586-019-1192-5. Epub 2019 May 15. Nature. 2019. PMID: 31092918 Free PMC article.
Amide-forming chemical ligation via O-acyl hydroxamic acids.
Dunkelmann DL, Hirata Y, Totaro KA, Cohen DT, Zhang C, Gates ZP, Pentelute BL. Dunkelmann DL, et al. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3752-3757. doi: 10.1073/pnas.1718356115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581295 Free PMC article.