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TLR9 and STING agonists cooperatively boost the immune response to SARS-CoV-2 RBD vaccine through an increased germinal center B cell response and reshaped T helper responses.
Yang JX, Tseng JC, Tien CF, Lee CY, Liu YL, Lin JJ, Tsai PJ, Liao HC, Liu SJ, Su YW, Hsu LC, Chen JK, Huang MH, Yu GY, Chuang TH. Yang JX, et al. Among authors: tien cf. Int J Biol Sci. 2023 May 29;19(9):2897-2913. doi: 10.7150/ijbs.81210. eCollection 2023. Int J Biol Sci. 2023. PMID: 37324951 Free PMC article.
Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection.
Lin JJ, Tien CF, Kuo YP, Lin EJ, Tsai WH, Chen MY, Tsai PJ, Su YW, Pathak N, Yang JM, Yu CY, Chuang ZS, Wu HC, Tsai WT, Dai SS, Liao HC, Chai KM, Su YS, Chuang TH, Liu SJ, Chen HW, Dou HY, Chen FJ, Chen CT, Liao CL, Yu GY. Lin JJ, et al. Among authors: tien cf. Front Immunol. 2022 May 2;13:872047. doi: 10.3389/fimmu.2022.872047. eCollection 2022. Front Immunol. 2022. PMID: 35585971 Free PMC article.