Wolf AJ - Search Results

1

Hexokinase dissociation from mitochondria promotes oligomerization of VDAC that facilitates NLRP3 inflammasome assembly and activation.

Baik SH, Ramanujan VK, Becker C, Fett S, Underhill DM, Wolf AJ. Baik SH, et al. Among authors: wolf aj. Sci Immunol. 2023 Jun 23;8(84):eade7652. doi: 10.1126/sciimmunol.ade7652. Epub 2023 Jun 16. Sci Immunol. 2023. PMID: 37327321 Free PMC article.

2

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.

Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. Shimada K, et al. Among authors: wolf aj. Immunity. 2012 Mar 23;36(3):401-14. doi: 10.1016/j.immuni.2012.01.009. Epub 2012 Feb 16. Immunity. 2012. PMID: 22342844 Free PMC article.

3

Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan.

Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Wolf AJ, et al. Cell. 2016 Jul 28;166(3):624-636. doi: 10.1016/j.cell.2016.05.076. Epub 2016 Jun 30. Cell. 2016. PMID: 27374331 Free PMC article.

4

Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion.

Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. Shimada T, et al. Among authors: wolf aj. Cell Host Microbe. 2010 Jan 21;7(1):38-49. doi: 10.1016/j.chom.2009.12.008. Cell Host Microbe. 2010. PMID: 20114027 Free PMC article.

5

Peptidoglycan recognition by the innate immune system.

Wolf AJ, Underhill DM. Wolf AJ, et al. Nat Rev Immunol. 2018 Apr;18(4):243-254. doi: 10.1038/nri.2017.136. Epub 2018 Jan 2. Nat Rev Immunol. 2018. PMID: 29292393 Review.

6

Malassezia spp. induce inflammatory cytokines and activate NLRP3 inflammasomes in phagocytes.

Wolf AJ, Limon JJ, Nguyen C, Prince A, Castro A, Underhill DM. Wolf AJ, et al. J Leukoc Biol. 2021 Jan;109(1):161-172. doi: 10.1002/JLB.2MA0820-259R. Epub 2020 Sep 17. J Leukoc Biol. 2021. PMID: 32941658 Free PMC article.

7

Differential use of CARD9 by dectin-1 in macrophages and dendritic cells.

Goodridge HS, Shimada T, Wolf AJ, Hsu YM, Becker CA, Lin X, Underhill DM. Goodridge HS, et al. Among authors: wolf aj. J Immunol. 2009 Jan 15;182(2):1146-54. doi: 10.4049/jimmunol.182.2.1146. J Immunol. 2009. PMID: 19124758 Free PMC article.

8

Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity.

Kaplan A, Ma J, Kyme P, Wolf AJ, Becker CA, Tseng CW, Liu GY, Underhill DM. Kaplan A, et al. Among authors: wolf aj. J Immunol. 2012 Nov 1;189(9):4537-45. doi: 10.4049/jimmunol.1201111. Epub 2012 Sep 24. J Immunol. 2012. PMID: 23008447 Free PMC article.

9

Poorly Cross-Linked Peptidoglycan in MRSA Due to mecA Induction Activates the Inflammasome and Exacerbates Immunopathology.

Müller S, Wolf AJ, Iliev ID, Berg BL, Underhill DM, Liu GY. Müller S, et al. Among authors: wolf aj. Cell Host Microbe. 2015 Nov 11;18(5):604-12. doi: 10.1016/j.chom.2015.10.011. Cell Host Microbe. 2015. PMID: 26567511 Free PMC article.

10

Inflammatory properties of antibiotic-treated bacteria.

Wolf AJ, Liu GY, Underhill DM. Wolf AJ, et al. J Leukoc Biol. 2017 Jan;101(1):127-134. doi: 10.1189/jlb.4MR0316-153RR. Epub 2016 Aug 30. J Leukoc Biol. 2017. PMID: 27576461 Free PMC article. Review.

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