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Page 1
Dimethyl itaconate induces long-term innate immune responses and confers protection against infection.
Ferreira AV, Kostidis S, Groh LA, Koeken VACM, Bruno M, Baydemir I, Kilic G, Bulut Ö, Andriopoulou T, Spanou V, Synodinou KD, Gkavogianni T, Moorlag SJCFM, Charlotte de Bree L, Mourits VP, Matzaraki V, Koopman WJH, van de Veerdonk FL, Renieris G, Giera M, Giamarellos-Bourboulis EJ, Novakovic B, Domínguez-Andrés J. Ferreira AV, et al. Cell Rep. 2023 Jun 27;42(6):112658. doi: 10.1016/j.celrep.2023.112658. Epub 2023 Jun 16. Cell Rep. 2023. PMID: 37330914 Free article.
Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis.
Domínguez-Andrés J, Arts RJW, Ter Horst R, Gresnigt MS, Smeekens SP, Ratter JM, Lachmandas E, Boutens L, van de Veerdonk FL, Joosten LAB, Notebaart RA, Ardavín C, Netea MG. Domínguez-Andrés J, et al. PLoS Pathog. 2017 Sep 18;13(9):e1006632. doi: 10.1371/journal.ppat.1006632. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28922415 Free PMC article.
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG. Domínguez-Andrés J, et al. Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4. Cell Metab. 2019. PMID: 30293776 Free article.
Itaconate as an immune modulator.
Ferreira AV, Netea MG, Domínguez-Andrés J. Ferreira AV, et al. Aging (Albany NY). 2019 Jun 24;11(12):3898-3899. doi: 10.18632/aging.102057. Aging (Albany NY). 2019. PMID: 31235675 Free PMC article. No abstract available.
The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan.
Keating ST, Groh L, van der Heijden CDCC, Rodriguez H, Dos Santos JC, Fanucchi S, Okabe J, Kaipananickal H, van Puffelen JH, Helder L, Noz MP, Matzaraki V, Li Y, de Bree LCJ, Koeken VACM, Moorlag SJCFM, Mourits VP, Domínguez-Andrés J, Oosting M, Bulthuis EP, Koopman WJH, Mhlanga M, El-Osta A, Joosten LAB, Netea MG, Riksen NP. Keating ST, et al. Cell Rep. 2020 Apr 21;31(3):107548. doi: 10.1016/j.celrep.2020.107548. Cell Rep. 2020. PMID: 32320649 Free PMC article.
Growth on Carbohydrates from Carbonaceous Meteorites Alters the Immunogenicity of Environment-Derived Bacterial Pathogens.
Domínguez-Andrés J, Eleveld M, Renieris G, Boltje TJ, Mesman RJ, van Niftrik L, Moons SJ, Rettberg P, van der Meer JWM, Giamarellos-Bourboulis EJ, Op den Camp HJM, de Jonge MI, Netea MG. Domínguez-Andrés J, et al. Astrobiology. 2020 Nov;20(11):1353-1362. doi: 10.1089/ast.2019.2173. Epub 2020 May 8. Astrobiology. 2020. PMID: 32391711
77 results