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Page 1
Fibrin drives thromboinflammation and neuropathology in COVID-19.
Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K. Ryu JK, et al. Among authors: suryawanshi rk. Nature. 2024 Sep;633(8031):905-913. doi: 10.1038/s41586-024-07873-4. Epub 2024 Aug 28. Nature. 2024. PMID: 39198643 Free PMC article.
The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2.
Suryawanshi RK, Jaishankar P, Correy GJ, Rachman MM, O'Leary PC, Taha TY, Zapatero-Belinchón FJ, McCavittMalvido M, Doruk YU, Stevens MGV, Diolaiti ME, Jogalekar MP, Richards AL, Montano M, Rosecrans J, Matthay M, Togo T, Gonciarz RL, Gopalkrishnan S, Neitz RJ, Krogan NJ, Swaney DL, Shoichet BK, Ott M, Renslo AR, Ashworth A, Fraser JS. Suryawanshi RK, et al. bioRxiv [Preprint]. 2024 Aug 29:2024.08.08.606661. doi: 10.1101/2024.08.08.606661. bioRxiv. 2024. PMID: 39149230 Free PMC article. Preprint.
NF-κB inhibitor alpha controls SARS-CoV-2 infection in ACE2-overexpressing human airway organoids.
Simoneau CR, Chen PY, Xing GK, Hayashi JM, Chen IP, Khalid MM, Meyers NL, Taha TY, Leon KE, Suryawanshi RK, McCavitt-Malvido M, Ashuach T, Fontaine KA, Rodriguez L, Joehnk B, Walcott K, Vasudevan S, Fang X, Maishan M, Schultz S, Roose JP, Matthay MA, Sil A, Arjomandi M, Yosef N, Ott M. Simoneau CR, et al. Among authors: suryawanshi rk. Sci Rep. 2024 Jul 4;14(1):15351. doi: 10.1038/s41598-024-66003-2. Sci Rep. 2024. PMID: 38961189 Free PMC article.
Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination.
Suryawanshi RK, Taha TY, McCavitt-Malvido M, Silva I, Khalid MM, Syed AM, Chen IP, Saldhi P, Sreekumar B, Montano M, Foresythe K, Tabata T, Kumar GR, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Kojima N, Arellanor T, Bussanich A, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Wang Y, Ghazarian S, Davis G, Rodriguez D, Doudna J, Spraggon L, Chiu CY, Ott M. Suryawanshi RK, et al. Emerg Microbes Infect. 2023 Dec;12(2):2270071. doi: 10.1080/22221751.2023.2270071. Epub 2023 Oct 31. Emerg Microbes Infect. 2023. PMID: 37869789 Free PMC article.
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.
Taha TY, Suryawanshi RK, Chen IP, Correy GJ, McCavitt-Malvido M, O'Leary PC, Jogalekar MP, Diolaiti ME, Kimmerly GR, Tsou CL, Gascon R, Montano M, Martinez-Sobrido L, Krogan NJ, Ashworth A, Fraser JS, Ott M. Taha TY, et al. Among authors: suryawanshi rk. PLoS Pathog. 2023 Aug 31;19(8):e1011614. doi: 10.1371/journal.ppat.1011614. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37651466 Free PMC article.
Post-acute immunological and behavioral sequelae in mice after Omicron infection.
Ma T, Suryawanshi RK, Miller SR, Ly KK, Thomas R, Elphick N, Yin K, Luo X, Kaliss N, Chen IP, Montano M, Sreekumar B, Standker L, Münch J, Heath Damron F, Palop JJ, Ott M, Roan NR. Ma T, et al. Among authors: suryawanshi rk. bioRxiv [Preprint]. 2023 Oct 4:2023.06.05.543758. doi: 10.1101/2023.06.05.543758. bioRxiv. 2023. PMID: 37333294 Free PMC article. Preprint.
Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication.
Bajaj T, Wehri E, Suryawanshi RK, King E, Pardeshi KS, Behrouzi K, Khodabakhshi Z, Schulze-Gahmen U, Kumar GR, Mofrad MRK, Nomura DK, Ott M, Schaletzky J, Murthy N. Bajaj T, et al. Among authors: suryawanshi rk. RSC Adv. 2023 Jun 12;13(26):17667-17677. doi: 10.1039/d3ra01915b. eCollection 2023 Jun 9. RSC Adv. 2023. PMID: 37312993 Free PMC article.
Mild SARS-CoV-2 infection results in long-lasting microbiota instability.
Upadhyay V, Suryawanshi RK, Tasoff P, McCavitt-Malvido M, Kumar RG, Murray VW, Noecker C, Bisanz JE, Hswen Y, Ha CWY, Sreekumar B, Chen IP, Lynch SV, Ott M, Lee S, Turnbaugh PJ. Upadhyay V, et al. Among authors: suryawanshi rk. mBio. 2023 Aug 31;14(4):e0088923. doi: 10.1128/mbio.00889-23. Epub 2023 Jun 9. mBio. 2023. PMID: 37294090 Free PMC article.
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo.
Taha TY, Suryawanshi RK, Chen IP, Correy GJ, O'Leary PC, Jogalekar MP, McCavitt-Malvido M, Diolaiti ME, Kimmerly GR, Tsou CL, Martinez-Sobrido L, Krogan NJ, Ashworth A, Fraser JS, Ott M. Taha TY, et al. Among authors: suryawanshi rk. bioRxiv [Preprint]. 2023 May 10:2023.04.18.537104. doi: 10.1101/2023.04.18.537104. bioRxiv. 2023. Update in: PLoS Pathog. 2023 Aug 31;19(8):e1011614. doi: 10.1371/journal.ppat.1011614 PMID: 37131711 Free PMC article. Updated. Preprint.
50 results