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Leveraging the use of in vitro and computational methods to support the development of enabling oral drug products: An InPharma commentary.
Reppas C, Kuentz M, Bauer-Brandl A, Carlert S, Dallmann A, Dietrich S, Dressman J, Ejskjaer L, Frechen S, Guidetti M, Holm R, Holzem FL, Karlsson Ε, Kostewicz E, Panbachi S, Paulus F, Senniksen MB, Stillhart C, Turner DB, Vertzoni M, Vrenken P, Zöller L, Griffin BT, O'Dwyer PJ. Reppas C, et al. Among authors: holm r. Eur J Pharm Sci. 2023 Sep 1;188:106505. doi: 10.1016/j.ejps.2023.106505. Epub 2023 Jun 19. Eur J Pharm Sci. 2023. PMID: 37343604 Free article.
In vitro models for the prediction of in vivo performance of oral dosage forms.
Kostewicz ES, Abrahamsson B, Brewster M, Brouwers J, Butler J, Carlert S, Dickinson PA, Dressman J, Holm R, Klein S, Mann J, McAllister M, Minekus M, Muenster U, Müllertz A, Verwei M, Vertzoni M, Weitschies W, Augustijns P. Kostewicz ES, et al. Among authors: holm r. Eur J Pharm Sci. 2014 Jun 16;57:342-66. doi: 10.1016/j.ejps.2013.08.024. Epub 2013 Aug 27. Eur J Pharm Sci. 2014. PMID: 23988843 Free article. Review.
Oral biopharmaceutics tools - time for a new initiative - an introduction to the IMI project OrBiTo.
Lennernäs H, Aarons L, Augustijns P, Beato S, Bolger M, Box K, Brewster M, Butler J, Dressman J, Holm R, Julia Frank K, Kendall R, Langguth P, Sydor J, Lindahl A, McAllister M, Muenster U, Müllertz A, Ojala K, Pepin X, Reppas C, Rostami-Hodjegan A, Verwei M, Weitschies W, Wilson C, Karlsson C, Abrahamsson B. Lennernäs H, et al. Among authors: holm r. Eur J Pharm Sci. 2014 Jun 16;57:292-9. doi: 10.1016/j.ejps.2013.10.012. Epub 2013 Nov 1. Eur J Pharm Sci. 2014. PMID: 24189462 Review.
Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs.
Bergström CA, Holm R, Jørgensen SA, Andersson SB, Artursson P, Beato S, Borde A, Box K, Brewster M, Dressman J, Feng KI, Halbert G, Kostewicz E, McAllister M, Muenster U, Thinnes J, Taylor R, Mullertz A. Bergström CA, et al. Among authors: holm r. Eur J Pharm Sci. 2014 Jun 16;57:173-99. doi: 10.1016/j.ejps.2013.10.015. Epub 2013 Nov 9. Eur J Pharm Sci. 2014. PMID: 24215735 Review.
In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.
Sjögren E, Abrahamsson B, Augustijns P, Becker D, Bolger MB, Brewster M, Brouwers J, Flanagan T, Harwood M, Heinen C, Holm R, Juretschke HP, Kubbinga M, Lindahl A, Lukacova V, Münster U, Neuhoff S, Nguyen MA, Peer Av, Reppas C, Hodjegan AR, Tannergren C, Weitschies W, Wilson C, Zane P, Lennernäs H, Langguth P. Sjögren E, et al. Among authors: holm r. Eur J Pharm Sci. 2014 Jun 16;57:99-151. doi: 10.1016/j.ejps.2014.02.010. Epub 2014 Mar 15. Eur J Pharm Sci. 2014. PMID: 24637348 Review.
Antibiotic Resistance: The Need For a Global Strategy.
Elder DP, Kuentz M, Holm R. Elder DP, et al. Among authors: holm r. J Pharm Sci. 2016 Aug;105(8):2278-87. doi: 10.1016/j.xphs.2016.06.002. Epub 2016 Jul 7. J Pharm Sci. 2016. PMID: 27397433
861 results