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Merging data curation and machine learning to improve nanomedicines.
Chen C, Yaari Z, Apfelbaum E, Grodzinski P, Shamay Y, Heller DA. Chen C, et al. Adv Drug Deliv Rev. 2022 Apr;183:114172. doi: 10.1016/j.addr.2022.114172. Epub 2022 Feb 18. Adv Drug Deliv Rev. 2022. PMID: 35189266 Free PMC article. Review.
Detection of ovarian cancer via the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine learning.
Kim M, Chen C, Wang P, Mulvey JJ, Yang Y, Wun C, Antman-Passig M, Luo HB, Cho S, Long-Roche K, Ramanathan LV, Jagota A, Zheng M, Wang Y, Heller DA. Kim M, et al. Among authors: chen c. Nat Biomed Eng. 2022 Mar;6(3):267-275. doi: 10.1038/s41551-022-00860-y. Epub 2022 Mar 17. Nat Biomed Eng. 2022. PMID: 35301449 Free PMC article.
Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo.
Kim M, Chen C, Yaari Z, Frederiksen R, Randall E, Wollowitz J, Cupo C, Wu X, Shah J, Worroll D, Lagenbacher RE, Goerzen D, Li YM, An H, Wang Y, Heller DA. Kim M, et al. Among authors: chen c. Nat Chem Biol. 2023 Dec;19(12):1448-1457. doi: 10.1038/s41589-023-01364-9. Epub 2023 Jun 15. Nat Chem Biol. 2023. PMID: 37322156 Free PMC article.
PRMT5 Inhibition Reduces Hyperinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis (HLH).
Brown-Burke F, Saadey R, Mao HCC, Marra P, Brooks E, Wandtke A, Hout I, Leon S, Sharma A, Yasin A, Cash T, Ahmed EH, Baiocchi EJ, Finoti SS, Zhang X, Bhagwat N, Vaddi K, Scherle P, Mozhenkova A, El-Ayachi I, Schenk AD, Sloan SL, Whitman K, Helmig-Mason J, Steyn S, Klimaszewski HL, Weist J, Weigel C, Koirala S, Alinari L, Snyder K, Ranganathan P, Chen CJ, Jordan MB, Baiocchi RA, Shindiapina P. Brown-Burke F, et al. Among authors: chen cj. Blood Adv. 2025 Jan 18:bloodadvances.2024013651. doi: 10.1182/bloodadvances.2024013651. Online ahead of print. Blood Adv. 2025. PMID: 39825858
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