Li J - Search Results

1

Discovery of potent heat shock protein 90 (Hsp90) inhibitors: structure-based virtual screening, molecular dynamics simulation, and biological evaluation.

Xu Y, Zou Y, Zhou S, Niu MM, Zhang Y, Li J, Xu Z, Yang L. Xu Y, et al. Among authors: li j. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2220558. doi: 10.1080/14756366.2023.2220558. J Enzyme Inhib Med Chem. 2023. PMID: 37357755 Free PMC article.

2

Dual-targeting cyclic peptides of receptor-binding domain (RBD) and main protease (Mpro) as potential drug leads for the treatment of SARS-CoV-2 infection.

Xu Z, Zou Y, Gao X, Niu MM, Li J, Xue L, Jiang S. Xu Z, et al. Among authors: li j. Front Pharmacol. 2022 Oct 19;13:1041331. doi: 10.3389/fphar.2022.1041331. eCollection 2022. Front Pharmacol. 2022. PMID: 36339564 Free PMC article.

3

Non-covalent cyclic peptides simultaneously targeting Mpro and NRP1 are highly effective against Omicron BA.2.75.

Yin S, Mei S, Li Z, Xu Z, Wu Y, Chen X, Liu D, Niu MM, Li J. Yin S, et al. Among authors: li z, li j. Front Pharmacol. 2022 Nov 2;13:1037993. doi: 10.3389/fphar.2022.1037993. eCollection 2022. Front Pharmacol. 2022. PMID: 36408220 Free PMC article.

4

Discovery of potent and noncovalent KRAS^G12D inhibitors: Structure-based virtual screening and biological evaluation.

Wang Y, Zhang H, Li J, Niu MM, Zhou Y, Qu Y. Wang Y, et al. Among authors: li j. Front Pharmacol. 2022 Dec 22;13:1094887. doi: 10.3389/fphar.2022.1094887. eCollection 2022. Front Pharmacol. 2022. PMID: 36618907 Free PMC article.

5

Discovery of dual S-RBD/NRP1-targeting peptides: structure-based virtual screening, synthesis, biological evaluation, and molecular dynamics simulation studies.

Hu C, Guo T, Zou Y, Gao J, Gao Y, Niu M, Xia Y, Shen X, Li J. Hu C, et al. Among authors: li j. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2212327. doi: 10.1080/14756366.2023.2212327. J Enzyme Inhib Med Chem. 2023. PMID: 37194732 Free PMC article.

6

Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents.

Liang S, Geng Y, Niu MM, Zhang Y, He W, Li J, Yang L, Xu Z. Liang S, et al. Among authors: li j. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2241118. doi: 10.1080/14756366.2023.2241118. J Enzyme Inhib Med Chem. 2023. PMID: 37528657 Free PMC article.

7

Highly potent dual-targeting angiotensin-converting enzyme 2 (ACE2) and Neuropilin-1 (NRP1) peptides: A promising broad-spectrum therapeutic strategy against SARS-CoV-2 infection.

Mei S, Zou Y, Jiang S, Xue L, Wang Y, Jing H, Yang P, Niu MM, Li J, Yuan K, Zhang Y. Mei S, et al. Among authors: li j. Eur J Med Chem. 2024 Jan 5;263:115908. doi: 10.1016/j.ejmech.2023.115908. Epub 2023 Oct 31. Eur J Med Chem. 2024. PMID: 37981444

8

UTP23 Is a Promising Prognostic Biomarker and Is Associated with Immune Infiltration in Breast Cancer.

Li J, Xie S, Zhang B, He W, Zhang Y, Wang J, Yang L. Li J, et al. Crit Rev Eukaryot Gene Expr. 2024;34(3):1-15. doi: 10.1615/CritRevEukaryotGeneExpr.2023048311. Crit Rev Eukaryot Gene Expr. 2024. PMID: 38305284

9

Discovery of a Potent Dual Son of Sevenless 1 (SOS1) and Epidermal Growth Factor Receptor (EGFR) Inhibitor for the Treatment of Prostate Cancer.

Zheng L, Zhang Y, Mei S, Xie T, Zou Y, Wang Y, Jing H, Xu S, Dramou P, Xu Z, Li J, Zhou Y, Niu MM. Zheng L, et al. Among authors: li j. J Med Chem. 2024 May 9;67(9):7130-7145. doi: 10.1021/acs.jmedchem.3c02433. Epub 2024 Apr 17. J Med Chem. 2024. PMID: 38630077

10

The identification of potent dual-target monopolar spindle 1 (MPS1) and histone deacetylase 8 (HDAC8) inhibitors through pharmacophore modeling, molecular docking, molecular dynamics simulations, and biological evaluation.

Hua H, Guan L, Pan B, Gao J, Geng Y, Niu MM, Li Z, Li J. Hua H, et al. Among authors: li z, li j. Front Pharmacol. 2024 Sep 16;15:1454523. doi: 10.3389/fphar.2024.1454523. eCollection 2024. Front Pharmacol. 2024. PMID: 39351092 Free PMC article.

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