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Page 1
Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation.
Zhou E, Ge X, Nakashima H, Li R, van der Zande HJP, Liu C, Li Z, Müller C, Bracher F, Mohammed Y, de Boer JF, Kuipers F, Guigas B, Glass CK, Rensen PCN, Giera M, Wang Y. Zhou E, et al. Among authors: glass ck. EMBO Mol Med. 2023 Aug 7;15(8):e16845. doi: 10.15252/emmm.202216845. Epub 2023 Jun 26. EMBO Mol Med. 2023. PMID: 37357756 Free PMC article.
The human milk oligosaccharide 3'sialyllactose reduces low-grade inflammation and atherosclerosis development in mice.
Pessentheiner AR, Spann NJ, Autran CA, Oh TG, Grunddal KV, Coker JK, Painter CD, Ramms B, Chiang AW, Wang CY, Hsiao J, Wang Y, Quach A, Booshehri LM, Hammond A, Tognaccini C, Latasiewicz J, Willemsen L, Zengler K, de Winther MP, Hoffman HM, Philpott M, Cribbs AP, Oppermann U, Lewis NE, Witztum JL, Yu R, Atkins AR, Downes M, Evans RM, Glass CK, Bode L, Gordts PL. Pessentheiner AR, et al. Among authors: glass ck. JCI Insight. 2024 Nov 8;9(21):e181329. doi: 10.1172/jci.insight.181329. JCI Insight. 2024. PMID: 39325548 Free PMC article.
Multi-Modal Analysis of human Hepatic Stellate Cells identifies novel therapeutic targets for Metabolic Dysfunction-Associated Steatotic Liver Disease.
Kim HY, Rosenthal SB, Liu X, Miciano C, Hou X, Miller M, Buchanan J, Poirion OB, Chilin-Fuentes D, Han C, Housseini M, Carvalho-Gontijo Weber R, Sakane S, Lee W, Zhao H, Diggle K, Preissl S, Glass CK, Ren B, Wang A, Brenner DA, Kisseleva T. Kim HY, et al. Among authors: glass ck. J Hepatol. 2024 Nov 8:S0168-8278(24)02667-9. doi: 10.1016/j.jhep.2024.10.044. Online ahead of print. J Hepatol. 2024. PMID: 39522884 Free article.
Neuroinflammation in Alzheimer disease.
Heneka MT, van der Flier WM, Jessen F, Hoozemanns J, Thal DR, Boche D, Brosseron F, Teunissen C, Zetterberg H, Jacobs AH, Edison P, Ramirez A, Cruchaga C, Lambert JC, Laza AR, Sanchez-Mut JV, Fischer A, Castro-Gomez S, Stein TD, Kleineidam L, Wagner M, Neher JJ, Cunningham C, Singhrao SK, Prinz M, Glass CK, Schlachetzki JCM, Butovsky O, Kleemann K, De Jaeger PL, Scheiblich H, Brown GC, Landreth G, Moutinho M, Grutzendler J, Gomez-Nicola D, McManus RM, Andreasson K, Ising C, Karabag D, Baker DJ, Liddelow SA, Verkhratsky A, Tansey M, Monsonego A, Aigner L, Dorothée G, Nave KA, Simons M, Constantin G, Rosenzweig N, Pascual A, Petzold GC, Kipnis J, Venegas C, Colonna M, Walter J, Tenner AJ, O'Banion MK, Steinert JR, Feinstein DL, Sastre M, Bhaskar K, Hong S, Schafer DP, Golde T, Ransohoff RM, Morgan D, Breitner J, Mancuso R, Riechers SP. Heneka MT, et al. Among authors: glass ck. Nat Rev Immunol. 2024 Dec 9. doi: 10.1038/s41577-024-01104-7. Online ahead of print. Nat Rev Immunol. 2024. PMID: 39653749 Review.
Human microglia maturation is underpinned by specific gene regulatory networks.
Han CZ, Li RZ, Hansen E, Trescott S, Fixsen BR, Nguyen CT, Mora CM, Spann NJ, Bennett HR, Poirion O, Buchanan J, Warden AS, Xia B, Schlachetzki JCM, Pasillas MP, Preissl S, Wang A, O'Connor C, Shriram S, Kim R, Schafer D, Ramirez G, Challacombe J, Anavim SA, Johnson A, Gupta M, Glass IA; Birth Defects Research Laboratory; Levy ML, Haim SB, Gonda DD, Laurent L, Hughes JF, Page DC, Blurton-Jones M, Glass CK, Coufal NG. Han CZ, et al. Among authors: glass ia, glass ck. Immunity. 2023 Sep 12;56(9):2152-2171.e13. doi: 10.1016/j.immuni.2023.07.016. Epub 2023 Aug 14. Immunity. 2023. PMID: 37582369 Free PMC article.
The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Zhong Y, Alberdi A, Massague J, Sun JC, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F. Deng Z, et al. Among authors: glass ck. Nature. 2024 Feb;626(8000):864-873. doi: 10.1038/s41586-023-06950-4. Epub 2024 Feb 7. Nature. 2024. PMID: 38326607 Free PMC article.
Deciphering microglia phenotypes in health and disease.
Balak CD, Han CZ, Glass CK. Balak CD, et al. Among authors: glass ck. Curr Opin Genet Dev. 2024 Feb;84:102146. doi: 10.1016/j.gde.2023.102146. Epub 2024 Jan 3. Curr Opin Genet Dev. 2024. PMID: 38171044 Free article. Review.
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2.
Ging K, Frick L, Schlachetzki J, Armani A, Zhu Y, Gilormini PA, Dhingra A, Böck D, Marques A, Deen M, Chen X, Serdiuk T, Trevisan C, Sellitto S, Pisano C, Glass CK, Heutink P, Yin JA, Vocadlo DJ, Aguzzi A. Ging K, et al. Among authors: glass ck. NPJ Parkinsons Dis. 2024 Oct 22;10(1):192. doi: 10.1038/s41531-024-00819-7. NPJ Parkinsons Dis. 2024. PMID: 39438499 Free PMC article.
399 results