Hoekstra M - Search Results

1

The impact of CYP2C19 genotype on phenoconversion by concomitant medication.

de Jong LM, Boussallami S, Sánchez-López E, Giera M, Tushuizen ME, Hoekstra M, Hawinkels LJAC, Rissmann R, Swen JJ, Manson ML. de Jong LM, et al. Among authors: hoekstra m. Front Pharmacol. 2023 Jun 8;14:1201906. doi: 10.3389/fphar.2023.1201906. eCollection 2023. Front Pharmacol. 2023. PMID: 37361233 Free PMC article.

2

Inhibition of PRMT3 activity reduces hepatic steatosis without altering atherosclerosis susceptibility in apoE knockout mice.

Hoekstra M, Nahon JE, de Jong LM, Kröner MJ, de Leeuw LR, Van Eck M. Hoekstra M, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1402-1409. doi: 10.1016/j.bbadis.2019.02.012. Epub 2019 Feb 15. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30776415 Free article.

3

PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice.

de Jong LM, Zhang Z, den Hartog Y, Sijsenaar TJP, Martins Cardoso R, Manson ML, Hankemeier T, Lindenburg PW, Salvatori DCF, Van Eck M, Hoekstra M. de Jong LM, et al. Among authors: hoekstra m. Sci Rep. 2022 Jan 10;12(1):483. doi: 10.1038/s41598-021-04524-w. Sci Rep. 2022. PMID: 35013582 Free PMC article.

4

LXR Agonist T0901317's Hepatic Impact Overrules Its Atheroprotective Action in Macrophages, Driving Early Atherogenesis in Chow-Diet-Fed Male Apolipoprotein E Knockout Mice.

Hoekstra M, de Jong LM, van der Geest R, de Leeuw LR, Krisnamurthi R, Geerling JJ, Van Eck M. Hoekstra M, et al. Biomolecules. 2024 Apr 2;14(4):429. doi: 10.3390/biom14040429. Biomolecules. 2024. PMID: 38672446 Free PMC article.

5

CYP P450 and non-CYP P450 Drug Metabolizing Enzyme Families Exhibit Differential Sensitivities towards Proinflammatory Cytokine Modulation.

de Jong LM, Harpal C, Berg DVD, Hoekstra M, Peter NJ, Rissmann R, Swen JJ, Manson ML. de Jong LM, et al. Among authors: hoekstra m. Drug Metab Dispos. 2024 Nov 15;52(12):1429-1437. doi: 10.1124/dmd.124.001867. Drug Metab Dispos. 2024. PMID: 39349298

6

Effects of pyrazole partial agonists on HCA(2) -mediated flushing and VLDL-triglyceride levels in mice.

Li Z, Blad CC, van der Sluis RJ, de Vries H, Van Berkel TJ, Ijzerman AP, Hoekstra M. Li Z, et al. Among authors: hoekstra m. Br J Pharmacol. 2012 Oct;167(4):818-25. doi: 10.1111/j.1476-5381.2012.02039.x. Br J Pharmacol. 2012. PMID: 22616721 Free PMC article.

7

Haloperidol inhibits the development of atherosclerotic lesions in LDL receptor knockout mice.

van der Sluis RJ, Nahon JE, Reuwer AQ, Van Eck M, Hoekstra M. van der Sluis RJ, et al. Among authors: hoekstra m. Br J Pharmacol. 2015 May;172(9):2397-405. doi: 10.1111/bph.13067. Epub 2015 Mar 16. Br J Pharmacol. 2015. PMID: 25572138 Free PMC article.

8

Inhibition of protein arginine methyltransferase 3 activity selectively impairs liver X receptor-driven transcription of hepatic lipogenic genes in vivo.

Nahon JE, Groeneveldt C, Geerling JJ, van Eck M, Hoekstra M. Nahon JE, et al. Among authors: hoekstra m. Br J Pharmacol. 2018 Aug;175(15):3175-3183. doi: 10.1111/bph.14361. Epub 2018 Jun 15. Br J Pharmacol. 2018. PMID: 29774529 Free PMC article.

9

Niacin reduces plasma CETP levels by diminishing liver macrophage content in CETP transgenic mice.

Li Z, Wang Y, van der Sluis RJ, van der Hoorn JW, Princen HM, Van Eck M, Van Berkel TJ, Rensen PC, Hoekstra M. Li Z, et al. Among authors: hoekstra m. Biochem Pharmacol. 2012 Sep 15;84(6):821-9. doi: 10.1016/j.bcp.2012.06.020. Epub 2012 Jun 27. Biochem Pharmacol. 2012. PMID: 22750059

10

Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development.

van der Stoep M, Li Z, Calpe-Berdiel L, van der Sluis RJ, Saleh P, McKinnon HJ, Smit MJ, Korporaal SJ, Van Berkel TJ, Van Eck M, Hoekstra M. van der Stoep M, et al. Among authors: hoekstra m. Biochem Pharmacol. 2013 Dec 1;86(11):1594-602. doi: 10.1016/j.bcp.2013.09.019. Epub 2013 Oct 2. Biochem Pharmacol. 2013. PMID: 24095721

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