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Identifying chemicals based on receptor binding/bioactivation/mechanistic explanation associated with potential to elicit hepatotoxicity and to support structure activity relationship-based read-across.
Wu S, Daston G, Rose J, Blackburn K, Fisher J, Reis A, Selman B, Naciff J. Wu S, et al. Among authors: blackburn k. Curr Res Toxicol. 2023 Jun 10;5:100108. doi: 10.1016/j.crtox.2023.100108. eCollection 2023. Curr Res Toxicol. 2023. PMID: 37363741 Free PMC article.
Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern.
Laufersweiler MC, Gadagbui B, Baskerville-Abraham IM, Maier A, Willis A, Scialli AR, Carr GJ, Felter SP, Blackburn K, Daston G. Laufersweiler MC, et al. Among authors: blackburn k. Regul Toxicol Pharmacol. 2012 Feb;62(1):160-82. doi: 10.1016/j.yrtph.2011.09.004. Epub 2011 Oct 10. Regul Toxicol Pharmacol. 2012. PMID: 22019814
Toward Good Read-Across Practice (GRAP) guidance.
Ball N, Cronin MT, Shen J, Blackburn K, Booth ED, Bouhifd M, Donley E, Egnash L, Hastings C, Juberg DR, Kleensang A, Kleinstreuer N, Kroese ED, Lee AC, Luechtefeld T, Maertens A, Marty S, Naciff JM, Palmer J, Pamies D, Penman M, Richarz AN, Russo DP, Stuard SB, Patlewicz G, van Ravenzwaay B, Wu S, Zhu H, Hartung T. Ball N, et al. Among authors: blackburn k. ALTEX. 2016;33(2):149-66. doi: 10.14573/altex.1601251. Epub 2016 Feb 11. ALTEX. 2016. PMID: 26863606 Free PMC article.
211 results