Jin M - Search Results

1

Activation of β₂-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms.

Jin M, Wei Z, Ramalingam N, Xiao M, Xu A, Yu X, Song Q, Liu W, Zhao J, Zhang D, Selkoe DJ, Li S. Jin M, et al. Mol Psychiatry. 2023 Nov;28(11):4877-4888. doi: 10.1038/s41380-023-02145-5. Mol Psychiatry. 2023. PMID: 37365243

2

Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.

Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ. Li S, et al. Among authors: jin m. J Neurosci. 2011 May 4;31(18):6627-38. doi: 10.1523/JNEUROSCI.0203-11.2011. J Neurosci. 2011. PMID: 21543591 Free PMC article.

3

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

Li S, Jin M, Zhang D, Yang T, Koeglsperger T, Fu H, Selkoe DJ. Li S, et al. Among authors: jin m. Neuron. 2013 Mar 6;77(5):929-41. doi: 10.1016/j.neuron.2012.12.040. Neuron. 2013. PMID: 23473322 Free PMC article.

4

Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol.

Jin M, Selkoe DJ. Jin M, et al. Neurobiol Dis. 2015 Oct;82:152-163. doi: 10.1016/j.nbd.2015.05.020. Epub 2015 Jun 6. Neurobiol Dis. 2015. PMID: 26054438 Free PMC article.

5

Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer's disease.

Li S, Jin M, Liu L, Dang Y, Ostaszewski BL, Selkoe DJ. Li S, et al. Among authors: jin m. Acta Neuropathol Commun. 2018 Nov 8;6(1):121. doi: 10.1186/s40478-018-0626-x. Acta Neuropathol Commun. 2018. PMID: 30409172 Free PMC article.

6

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Hong S, Ostaszewski BL, Yang T, O'Malley TT, Jin M, Yanagisawa K, Li S, Bartels T, Selkoe DJ. Hong S, et al. Among authors: jin m. Neuron. 2014 Apr 16;82(2):308-19. doi: 10.1016/j.neuron.2014.02.027. Epub 2014 Mar 27. Neuron. 2014. PMID: 24685176 Free PMC article.

7

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration.

Jin M, Shepardson N, Yang T, Chen G, Walsh D, Selkoe DJ. Jin M, et al. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5819-24. doi: 10.1073/pnas.1017033108. Epub 2011 Mar 18. Proc Natl Acad Sci U S A. 2011. PMID: 21421841 Free PMC article.

8

An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer's disease.

Jin M, O'Nuallain B, Hong W, Boyd J, Lagomarsino VN, O'Malley TT, Liu W, Vanderburg CR, Frosch MP, Young-Pearse T, Selkoe DJ, Walsh DM. Jin M, et al. Nat Commun. 2018 Jul 11;9(1):2676. doi: 10.1038/s41467-018-05068-w. Nat Commun. 2018. PMID: 29992960 Free PMC article.

9

Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics.

Wang Z, Jin M, Hong W, Liu W, Reczek D, Lagomarsino VN, Hu Y, Weeden T, Frosch MP, Young-Pearse TL, Pradier L, Selkoe D, Walsh DM. Wang Z, et al. Among authors: jin m. Acta Neuropathol Commun. 2023 Mar 10;11(1):39. doi: 10.1186/s40478-023-01511-2. Acta Neuropathol Commun. 2023. PMID: 36899414 Free PMC article.

10

Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies.

Sanderson JB, De S, Jiang H, Rovere M, Jin M, Zaccagnini L, Hays Watson A, De Boni L, Lagomarsino VN, Young-Pearse TL, Liu X, Pochapsky TC, Hyman BT, Dickson DW, Klenerman D, Selkoe DJ, Bartels T. Sanderson JB, et al. Among authors: jin m. Brain Commun. 2020;2(1):fcaa010. doi: 10.1093/braincomms/fcaa010. Epub 2020 Feb 11. Brain Commun. 2020. PMID: 32280944 Free PMC article.

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