Selkoe DJ - Search Results

1

Activation of β₂-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms.

Jin M, Wei Z, Ramalingam N, Xiao M, Xu A, Yu X, Song Q, Liu W, Zhao J, Zhang D, Selkoe DJ, Li S. Jin M, et al. Among authors: selkoe dj. Mol Psychiatry. 2023 Nov;28(11):4877-4888. doi: 10.1038/s41380-023-02145-5. Mol Psychiatry. 2023. PMID: 37365243

2

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ. Shankar GM, et al. Among authors: selkoe dj. Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782. Epub 2008 Jun 22. Nat Med. 2008. PMID: 18568035 Free PMC article.

3

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake.

Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Li S, et al. Neuron. 2009 Jun 25;62(6):788-801. doi: 10.1016/j.neuron.2009.05.012. Neuron. 2009. PMID: 19555648 Free PMC article.

4

How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity?

Li S, Shankar GM, Selkoe DJ. Li S, et al. Among authors: selkoe dj. Front Cell Neurosci. 2010 Mar 19;4:5. doi: 10.3389/fncel.2010.00005. eCollection 2010. Front Cell Neurosci. 2010. PMID: 20428510 Free PMC article. No abstract available.

5

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration.

Jin M, Shepardson N, Yang T, Chen G, Walsh D, Selkoe DJ. Jin M, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5819-24. doi: 10.1073/pnas.1017033108. Epub 2011 Mar 18. Proc Natl Acad Sci U S A. 2011. PMID: 21421841 Free PMC article.

6

Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors.

Li S, Jin M, Koeglsperger T, Shepardson NE, Shankar GM, Selkoe DJ. Li S, et al. Among authors: selkoe dj. J Neurosci. 2011 May 4;31(18):6627-38. doi: 10.1523/JNEUROSCI.0203-11.2011. J Neurosci. 2011. PMID: 21543591 Free PMC article.

7

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

Li S, Jin M, Zhang D, Yang T, Koeglsperger T, Fu H, Selkoe DJ. Li S, et al. Among authors: selkoe dj. Neuron. 2013 Mar 6;77(5):929-41. doi: 10.1016/j.neuron.2012.12.040. Neuron. 2013. PMID: 23473322 Free PMC article.

8

Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS.

Koeglsperger T, Li S, Brenneis C, Saulnier JL, Mayo L, Carrier Y, Selkoe DJ, Weiner HL. Koeglsperger T, et al. Among authors: selkoe dj. Glia. 2013 Jun;61(6):985-1002. doi: 10.1002/glia.22490. Epub 2013 Mar 28. Glia. 2013. PMID: 23536313 Free PMC article.

9

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Hong S, Ostaszewski BL, Yang T, O'Malley TT, Jin M, Yanagisawa K, Li S, Bartels T, Selkoe DJ. Hong S, et al. Among authors: selkoe dj. Neuron. 2014 Apr 16;82(2):308-19. doi: 10.1016/j.neuron.2014.02.027. Epub 2014 Mar 27. Neuron. 2014. PMID: 24685176 Free PMC article.

10

Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol.

Jin M, Selkoe DJ. Jin M, et al. Among authors: selkoe dj. Neurobiol Dis. 2015 Oct;82:152-163. doi: 10.1016/j.nbd.2015.05.020. Epub 2015 Jun 6. Neurobiol Dis. 2015. PMID: 26054438 Free PMC article.

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