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Nuclear Factor Erythroid 2 Related Factor 2 Activator JC-5411 Inhibits Atherosclerosis Through Suppression of Inflammation and Regulation of Lipid Metabolism.
Jiang X, Li Y, Wang W, Han X, Han J, Chen M, Zhang J, Wang C, Li S, Luo J, Wang X, Xu Y, Xu Y, Cheng J, Si S. Jiang X, et al. Among authors: wang x, wang w, wang c. Front Pharmacol. 2020 Nov 16;11:532568. doi: 10.3389/fphar.2020.532568. eCollection 2020. Front Pharmacol. 2020. PMID: 33442380 Free PMC article.
A pan-PPAR agonist E17241 ameliorates hyperglycemia and diabetic dyslipidemia in KKAy mice via up-regulating ABCA1 in islet, liver, and white adipose tissue.
Sheng R, Li Y, Wu Y, Liu C, Wang W, Han X, Li Y, Lei L, Jiang X, Zhang Y, Zhang Y, Li S, Hong B, Liu C, Xu Y, Si S. Sheng R, et al. Among authors: wang w. Biomed Pharmacother. 2024 Mar;172:116220. doi: 10.1016/j.biopha.2024.116220. Epub 2024 Feb 2. Biomed Pharmacother. 2024. PMID: 38308968 Free article.
The novel small molecule E0924G dually regulates bone formation and bone resorption through activating the PPARδ signaling pathway to prevent bone loss in ovariectomized rats and senile mice.
Li Y, Liu C, Han X, Sheng R, Bao L, Lei L, Wu Y, Li Q, Zhang Y, Zhang J, Wang W, Zhang Y, Li S, Wang C, Wei X, Wang J, Peng Z, Xu Y, Si S. Li Y, et al. Among authors: wang w, wang j, wang c. Bioorg Chem. 2024 Jun;147:107364. doi: 10.1016/j.bioorg.2024.107364. Epub 2024 Apr 11. Bioorg Chem. 2024. PMID: 38636434
Antirheumatic drug leflunomide attenuates atherosclerosis by regulating lipid metabolism and endothelial dysfunction via DHODH/AMPK signaling pathway.
Jiang X, Wang W, Lei L, Feng T, Hu Y, Liu P, Li Y, Sheng R, Zhang Y, Li S, Zhang J, Zhang Y, Jin ZG, Tian Z, Jiang J, Xu Y, Si S. Jiang X, et al. Among authors: wang w. Int J Biol Sci. 2024 Jul 2;20(10):3725-3741. doi: 10.7150/ijbs.93465. eCollection 2024. Int J Biol Sci. 2024. PMID: 39113703 Free PMC article.
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