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929 results

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Clinical Activity and Exploratory Resistance Mechanism of Milademetan, an MDM2 Inhibitor, in Intimal Sarcoma with MDM2 Amplification: An Open-Label Phase Ib/II Study.
Koyama T, Shimizu T, Kojima Y, Sudo K, Okuma HS, Shimoi T, Ichikawa H, Kohsaka S, Sadachi R, Hirakawa A, Yoshida A, Ando RM, Ueno T, Yanagaki M, Matsui N, Nakamura K, Yamamoto N, Yonemori K. Koyama T, et al. Among authors: kohsaka s. Cancer Discov. 2023 Aug 4;13(8):1814-1825. doi: 10.1158/2159-8290.CD-23-0419. Cancer Discov. 2023. PMID: 37369013 Clinical Trial.
Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation.
Hayakawa D, Takahashi F, Mitsuishi Y, Tajima K, Hidayat M, Winardi W, Ihara H, Kanamori K, Matsumoto N, Asao T, Ko R, Shukuya T, Takamochi K, Hayashi T, Suehara Y, Takeda Nakamura I, Ueno T, Kohsaka S, Mano H, Takahashi K. Hayakawa D, et al. Among authors: kohsaka s. Thorac Cancer. 2020 Jan;11(1):140-149. doi: 10.1111/1759-7714.13255. Epub 2019 Nov 22. Thorac Cancer. 2020. PMID: 31758670 Free PMC article.
Assessment of Predictive Biomarkers of the Response to Pazopanib Based on an Integrative Analysis of High-grade Soft-tissue Sarcomas: Analysis of a Tumor Sample from a Responder and Patients with Other Soft-tissue Sarcomas.
Suehara Y, Kohsaka S, Yamaguchi S, Hayashi T, Kurihara T, Sano K, Sasa K, Akaike K, Ueno T, Kojima S, Ikegami M, Mizuno S, Okubo T, Kim Y, Kaneko K, Saito T, Kato S, Mano H. Suehara Y, et al. Among authors: kohsaka s. Clin Orthop Relat Res. 2020 Nov;478(11):2461-2476. doi: 10.1097/CORR.0000000000001322. Clin Orthop Relat Res. 2020. PMID: 32567826 Free PMC article.
Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma.
Suehara Y, Kohsaka S, Hayashi T, Akaike K, Kurisaki-Arakawa A, Sato S, Kobayashi E, Mizuno S, Ueno T, Morii T, Okuma T, Kurihara T, Hasegawa N, Sano K, Sasa K, Okubo T, Kim Y, Mano H, Saito T. Suehara Y, et al. Among authors: kohsaka s. Clin Orthop Relat Res. 2021 Apr 1;479(4):838-852. doi: 10.1097/CORR.0000000000001548. Clin Orthop Relat Res. 2021. PMID: 33196586 Free PMC article.
Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level.
Nakamura IT, Ikegami M, Hasegawa N, Hayashi T, Ueno T, Kawazu M, Yagishita S, Goto Y, Shinno Y, Kojima Y, Takamochi K, Takahashi F, Takahashi K, Mano H, Kohsaka S. Nakamura IT, et al. Among authors: kohsaka s. Cancer Sci. 2021 May;112(5):2006-2019. doi: 10.1111/cas.14821. Epub 2021 Apr 2. Cancer Sci. 2021. PMID: 33484069 Free PMC article.
Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA.
Sunami K, Bando H, Yatabe Y, Naito Y, Takahashi H, Tsuchihara K, Toyooka S, Mimori K, Kohsaka S, Uetake H, Kinoshita I, Komine K, Takeda M, Hayashida T, Tamura K, Nishio K, Yamamoto N; Working Group of a Joint Task Force of Three Academic Societies for the Promotion of Cancer Genomic Medicine. Sunami K, et al. Among authors: kohsaka s. Cancer Sci. 2021 Sep;112(9):3911-3917. doi: 10.1111/cas.15022. Epub 2021 Jul 12. Cancer Sci. 2021. PMID: 34128569 Free PMC article.
Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers.
Hasegawa N, Kohsaka S, Kurokawa K, Shinno Y, Takeda Nakamura I, Ueno T, Kojima S, Kawazu M, Suehara Y, Ishijima M, Goto Y, Kojima Y, Yonemori K, Hayashi T, Saito T, Shukuya T, Takahashi F, Takahashi K, Mano H. Hasegawa N, et al. Among authors: kohsaka s. Cancer Sci. 2021 Oct;112(10):4393-4403. doi: 10.1111/cas.15084. Epub 2021 Aug 18. Cancer Sci. 2021. PMID: 34310819 Free PMC article.
929 results